CXCL13 Protein (AA 23-109) (His-SUMO Tag)

N° du produit ABIN7274442

Détail du produit

Antigène: CXCL13 (Chemokine (C-X-C Motif) Ligand 13 (CXCL13))

Type de proteíne: Recombinant

Attributs du protein: AA 23-109

Origine: Humain

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette CXCL13 protéine est marqué à la His-SUMO Tag.

Fonction: Human CXCL13/BCA-1 Protein

Séquence: Val23-Pro109

Attributs du produit: Recombinant Human CXCL13/BCA-1 Protein is expressed from E.coli with His tag and Sumo tag at the N-Terminus.It contains Val23-Pro109.

Pureté: > 95 % as determined by Tris-Bis PAGE

Stérilité: 0.22 μm filtered

niveau d'endotoxine: Less than 1EU per μg by the LAL method.

Biological Activity Comment: Immobilized Anti-CXCL13 Antibody, hFc Tag at 5μg/ml (100μl/well) on the plate. Dose response curve for Human CXCL13, His Tag with the EC50 of 0.54μg/ml determined by ELISA. See testing image for detail.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Supplied as 0.22μm filtered solution in 0.1M Glycine, 0.3M NaCl, 0.2M L-arginine, 10 % Glycerol ( pH 3.0).

Stock: -80 °C

Stockage commentaire: Valid for 12 months from date of receipt when stored at -80°C., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Date de péremption: 12 months

Détail du antigène

Antigène: CXCL13 (Chemokine (C-X-C Motif) Ligand 13 (CXCL13))

Autre désignation: CXCL13 (CXCL13 Produits)

Synonymes: 4631412M08Rik Protein, ANGIE2 Protein, Angie Protein, BCA-1 Protein, BLC Protein, BLR1L Protein, Scyb13 Protein, ANGIE Protein, BCA1 Protein, SCYB13 Protein, C-X-C motif chemokine ligand 13 Protein, chemokine (C-X-C motif) ligand 13 Protein, Cxcl13 Protein, CXCL13 Protein

Sujet: Recent studies have implicated chemokines in microglial activation and pathogenesis of neuropathic pain. C-X-C motif chemokine 13 (CXCL13) is a B lymphocyte chemoattractant that activates CXCR5. Using the spinal nerve ligation (SNL) model of neuropathic pain, CXCL13 was persistently upregulated in spinal cord neurons after SNL, resulting in spinal astrocyte activation via CXCR5 in mice.

Poids moléculaire: 22.9 kDa. The protein migrates to 26-28 kDa based on Tris-Bis PAGE result.

UniProt: O43927