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CXCL13 Protein (AA 23-109) (His-SUMO Tag)

CXCL13 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 95 % as determined by Tris-Bis PAGE
N° du produit ABIN7274442
  • Antigène Voir toutes CXCL13 Protéines
    CXCL13 (Chemokine (C-X-C Motif) Ligand 13 (CXCL13))
    Type de proteíne
    Recombinant
    Attributs du protein
    AA 23-109
    Origine
    • 11
    • 7
    • 3
    • 1
    • 1
    Humain
    Source
    • 16
    • 3
    • 2
    Escherichia coli (E. coli)
    Purification/Conjugué
    Cette CXCL13 protéine est marqué à la His-SUMO Tag.
    Fonction
    Human CXCL13/BCA-1 Protein
    Séquence
    Val23-Pro109
    Attributs du produit
    Recombinant Human CXCL13/BCA-1 Protein is expressed from E.coli with His tag and Sumo tag at the N-Terminus.It contains Val23-Pro109.
    Pureté
    > 95 % as determined by Tris-Bis PAGE
    Stérilité
    0.22 μm filtered
    niveau d'endotoxine
    Less than 1EU per μg by the LAL method.
    Biological Activity Comment
    Immobilized Anti-CXCL13 Antibody, hFc Tag at 5μg/ml (100μl/well) on the plate. Dose response curve for Human CXCL13, His Tag with the EC50 of 0.54μg/ml determined by ELISA. See testing image for detail.
    Top Product
    Discover our top product CXCL13 Protéine
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Supplied as 0.22μm filtered solution in 0.1M Glycine, 0.3M NaCl, 0.2M L-arginine, 10 % Glycerol ( pH 3.0).
    Stock
    -80 °C
    Stockage commentaire
    Valid for 12 months from date of receipt when stored at -80°C., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    CXCL13 (Chemokine (C-X-C Motif) Ligand 13 (CXCL13))
    Autre désignation
    CXCL13 (CXCL13 Produits)
    Synonymes
    4631412M08Rik Protein, ANGIE2 Protein, Angie Protein, BCA-1 Protein, BLC Protein, BLR1L Protein, Scyb13 Protein, ANGIE Protein, BCA1 Protein, SCYB13 Protein, C-X-C motif chemokine ligand 13 Protein, chemokine (C-X-C motif) ligand 13 Protein, Cxcl13 Protein, CXCL13 Protein
    Sujet
    Recent studies have implicated chemokines in microglial activation and pathogenesis of neuropathic pain. C-X-C motif chemokine 13 (CXCL13) is a B lymphocyte chemoattractant that activates CXCR5. Using the spinal nerve ligation (SNL) model of neuropathic pain, CXCL13 was persistently upregulated in spinal cord neurons after SNL, resulting in spinal astrocyte activation via CXCR5 in mice.
    Poids moléculaire
    22.9 kDa. The protein migrates to 26-28 kDa based on Tris-Bis PAGE result.
    UniProt
    O43927
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