CXCL13 Protein (AA 23-109) (Fc Tag)
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- Antigène Voir toutes CXCL13 Protéines
- CXCL13 (Chemokine (C-X-C Motif) Ligand 13 (CXCL13))
- Type de proteíne
- Recombinant
- Attributs du protein
- AA 23-109
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Origine
- Humain
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette CXCL13 protéine est marqué à la Fc Tag.
- Fonction
- Human CXCL13/BCA-1 Protein
- Séquence
- Val23-Per109
- Attributs du produit
- Recombinant Human CXCL13/BCA-1 Protein is expressed from HEK293 with hFc tag at the N-Terminus.It contains Val23-Per109.
- Pureté
- > 95 % as determined by Tris-Bis PAGE
- Stérilité
- 0.22 μm filtered
- niveau d'endotoxine
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- Immobilized Human CXCL13, hFc Tag at 0.5μg/ml (100μl/well) on the plate. Dose response curve for Biotinylated Anti-CXCL13 Antibody, hFc Tag with the EC50 of 17.2ng/ml determined by ELISA. See testing image for detail.
- Top Product
- Discover our top product CXCL13 Protéine
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Supplied as 0.22μm filtered solution in 50 mM Tris,500 mM NaCl ( pH 7.4).
- Stock
- -80 °C
- Stockage commentaire
- Valid for 12 months from date of receipt when stored at -80°C., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- CXCL13 (Chemokine (C-X-C Motif) Ligand 13 (CXCL13))
- Autre désignation
- CXCL13 (CXCL13 Produits)
- Synonymes
- 4631412M08Rik Protein, ANGIE2 Protein, Angie Protein, BCA-1 Protein, BLC Protein, BLR1L Protein, Scyb13 Protein, ANGIE Protein, BCA1 Protein, SCYB13 Protein, C-X-C motif chemokine ligand 13 Protein, chemokine (C-X-C motif) ligand 13 Protein, Cxcl13 Protein, CXCL13 Protein
- Sujet
- Recent studies have implicated chemokines in microglial activation and pathogenesis of neuropathic pain. C-X-C motif chemokine 13 (CXCL13) is a B lymphocyte chemoattractant that activates CXCR5. Using the spinal nerve ligation (SNL) model of neuropathic pain, CXCL13 was persistently upregulated in spinal cord neurons after SNL, resulting in spinal astrocyte activation via CXCR5 in mice.
- Poids moléculaire
- 37.6 kDa. Due to glycosylation, the protein migrates to 40-50 kDa based on Tris-Bis PAGE result.
- UniProt
- O43927
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