EPH Receptor A10 Protein (EPHA10) (AA 23-565) (His tag)

N° du produit ABIN7274562

Détail du produit

Antigène: EPH Receptor A10 (EPHA10)

Type de proteíne: Recombinant

Attributs du protein: AA 23-565

Origine: Souris

Source: HEK-293 Cells

Purification/Conjugué: Cette EPH Receptor A10 protéine est marqué à la His tag.

Fonction: Mouse EPHA10 Protein

Séquence: Leu23-Ala565

Attributs du produit: Recombinant Mouse EPHA10 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Leu23-Ala565.

Pureté: > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Stérilité: 0.22 μm filtered

niveau d'endotoxine: Less than 1EU per μg by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Stock: -20 °C,-80 °C

Stockage commentaire: -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Date de péremption: 12 months

Détail du antigène

Antigène: EPH Receptor A10 (EPHA10)

Autre désignation: EPHA10 (EPHA10 Produits)

Synonymes: A330090H18 Protein, RGD1562679 Protein, EPH receptor A10 Protein, Eph receptor A10 Protein, EPHA10 Protein, Epha10 Protein

Sujet: EphA10 (erythropoietin-producing hepatocellular carcinoma receptor A10) is a catalytically defective receptor protein tyrosine kinase in the ephrin receptor family.EphA10 was elevated and higher in tumor tissues than in normal tissues in some cancer types, including pancreatic cancer.EphA10 silencing reduced the proliferation, migration, and adhesion of MIA PaCa-2 and AsPC-1 pancreatic cancer cells. EphA10 plays a pivotal role in the tumorigenesis of pancreatic epithelial cells and is a novel therapeutic target for pancreatic cancer.

Poids moléculaire: 59.6 kDa. Due to glycosylation, the protein migrates to 68-80 kDa based on Tris-Bis PAGE result.

Pathways: Signalisation RTK