CD42b Protein (AA 17-531) (His tag)

N° du produit ABIN7274755

Détail du produit

Antigène: CD42b (GP1BA) (Glycoprotein Ib (Platelet), alpha Polypeptide (GP1BA))

Type de proteíne: Recombinant

Attributs du protein: AA 17-531

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette CD42b protéine est marqué à la His tag.

Fonction: Human CD42b/GP1BA Protein

Séquence: His17-Leu531

Attributs du produit: Recombinant Human CD42b/GP1BA Protein is expressed from HEK293 with His tag at the C-Terminus.It contains His17-Leu531.

Pureté: > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Stérilité: 0.22 μm filtered

niveau d'endotoxine: Less than 1EU per μg by the LAL method.

Biological Activity Comment: Immobilized Human CD42b, His Tag at 0.2μg/ml (100μl/well) on the plate. Dose response curve for Anti-CD42b Antibody, hFc Tag with the EC50 of 8.9ng/ml determined by ELISA. See testing image for detail.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Stock: -20 °C,-80 °C

Stockage commentaire: -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Date de péremption: 12 months

Détail du antigène

Antigène: CD42b (GP1BA) (Glycoprotein Ib (Platelet), alpha Polypeptide (GP1BA))

Autre désignation: CD42b (GP1BA Produits)

Synonymes: BDPLT1 Protein, BDPLT3 Protein, BSS Protein, CD42B Protein, CD42b-alpha Protein, DBPLT3 Protein, GP1B Protein, GPIbA Protein, VWDP Protein, GP1BA Protein, GPIba Protein, GPIbalpha Protein, glycoprotein Ib platelet alpha subunit Protein, glycoprotein Ib (platelet), alpha polypeptide Protein, glycoprotein 1b, alpha polypeptide Protein, GP1BA Protein, Gp1ba Protein

Sujet: Absence of the CD42 complex leads to the Bernard-Soulier syndrome (BSS), which is a bleeding disorder characterized by thrombocytopenia and giant platelets. So far, mutations have been found in the genes encoding CD42a, CD42b and CD42c in patients with BSS**.

Poids moléculaire: 57.6 kDa. Due to glycosylation, the protein migrates to 110-115 kDa based on Tris-Bis PAGE result.

UniProt: P07359