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IL-25 Protein (AA 33-177) (His-Avi Tag,Biotin)

IL25 Origine: Humain Hôte: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
N° du produit ABIN7274923
  • Antigène Voir toutes IL-25 (IL25) Protéines
    IL-25 (IL25) (Interleukin 25 (IL25))
    Type de proteíne
    Recombinant
    Attributs du protein
    AA 33-177
    Origine
    • 15
    • 11
    • 4
    Humain
    Source
    • 18
    • 7
    • 3
    • 1
    HEK-293 Cells
    Purification/Conjugué
    Cette IL-25 protéine est marqué à la His-Avi Tag,Biotin.
    Fonction
    Biotinylated Human IL-25/IL-17E Protein
    Séquence
    Tyr33-Gly177
    Attributs du produit
    Recombinant Biotinylated Human IL-25/IL-17E Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Tyr33-Gly177.
    Pureté
    > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
    Stérilité
    0.22 μm filtered
    niveau d'endotoxine
    Less than 1EU per μg by the LAL method.
    Biological Activity Comment
    Immobilized Human IL-17RB, His Tag at 5μg/ml (100μl/well) on the plate. Dose response curve for Biotinylated Human IL-25, His Tag with the EC50 of 58.5ng/ml determined by ELISA. See testing image for detail.
    Top Product
    Discover our top product IL25 Protéine
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Supplied as 0.22μm filtered solution in PBS ( pH 7.4).
    Stock
    -80 °C
    Stockage commentaire
    Valid for 12 months from date of receipt when stored at -80°C., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    IL-25 (IL25) (Interleukin 25 (IL25))
    Autre désignation
    IL-25 (IL25 Produits)
    Synonymes
    IL17E Protein, IL-17e Protein, Il17e Protein, IL25 Protein, RGD1561632 Protein, interleukin 25 Protein, IL25 Protein, Il25 Protein
    Sujet
    IL-25, also known as IL-17E, is a member of the IL-17 cytokine family mostly produced by epithelial cells and innate immune cells. After binding to the IL-17RB/IL-17RA complex, IL-25 induces downstream signaling responses in epithelial cells and type 2 lymphocytes, which initiates, propagates, and sustains type 2 immunity. The function of IL-25 in allergic diseases such as asthma has been well established, and now also is extended to diseases such as inflammatory bowel disease and cancer.
    Poids moléculaire
    19.24 kDa. Due to glycosylation, the protein migrates to 25-35 kDa based on Tris-Bis PAGE result.
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