IL22 Receptor alpha 1 Protein (AA 18-225) (His tag)

N° du produit ABIN7275008

Détail du produit

Antigène: IL22 Receptor alpha 1 (IL22RA1) (Interleukin 22 Receptor, alpha 1 (IL22RA1))

Type de proteíne: Recombinant

Attributs du protein: AA 18-225

Origine: Cynomolgus

Source: HEK-293 Cells

Purification/Conjugué: Cette IL22 Receptor alpha 1 protéine est marqué à la His tag.

Fonction: Cynomolgus IL-22R alpha 1 Protein

Séquence: Pro18-Thr225

Attributs du produit: Recombinant Cynomolgus IL-22R alpha 1 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Pro18-Thr225.

Pureté: > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Stérilité: 0.22 μm filtered

niveau d'endotoxine: Less than 1EU per μg by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Stock: -20 °C,-80 °C

Stockage commentaire: -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Date de péremption: 12 months

Détail du antigène

Antigène: IL22 Receptor alpha 1 (IL22RA1) (Interleukin 22 Receptor, alpha 1 (IL22RA1))

Autre désignation: IL-22R alpha 1 (IL22RA1 Produits)

Synonymes: IL22RA1 Protein, CRF2-9 Protein, IL22R Protein, IL22R1 Protein, 9130219A07Rik Protein, ENSMUSG00000073746 Protein, IL-22R Protein, Il22r Protein, RGD1559655 Protein, interleukin 22 receptor subunit alpha 1 Protein, interleukin 22 receptor, alpha 1 Protein, IL22RA1 Protein, Il22ra1 Protein

Sujet: IL-22 receptor, also known as IL-22 R alpha 1 and CRF2-9, is an approximately 65 kDa transmembrane glycoprotein in the type II cytokine receptor family (CRF).Component of the receptor for IL20, IL22 and IL24. Component of IL22 receptor formed by IL22RA1 and IL10RB enabling IL22 signaling via JAK/STAT pathways. IL22 also induces activation of MAPK1/MAPK3 and Akt kinases pathways. Component of one of the receptor for IL20 and IL24 formed by IL22RA1 and IL20RB also signaling through STATs activation. Mediates IL24 antiangiogenic activity as well as IL24 inhibitory effect on endothelial cell tube formation and differentiation.

Poids moléculaire: 24.84 kDa. Due to glycosylation, the protein migrates to 38-45 kDa based on Tris-Bis PAGE result.

UniProt: A0A2K5TKX9