MUC1 Protein (AA 24-158) (Fc Tag)

N° du produit ABIN7275298

Détail du produit

Antigène: MUC1 (Mucin 1 (MUC1))

Type de proteíne: Recombinant

Attributs du protein: AA 24-158

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette MUC1 protéine est marqué à la Fc Tag.

Fonction: Human MUC1 Isoform Y Protein

Séquence: Ser24-Gly158

Attributs du produit: Recombinant Human MUC1 Isoform Y Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Ser24-Gly158.

Pureté: > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Stérilité: 0.22 μm filtered

niveau d'endotoxine: Less than 1EU per μg by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Stock: -20 °C,-80 °C

Stockage commentaire: -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Date de péremption: 12 months

Détail du antigène

Antigène: MUC1 (Mucin 1 (MUC1))

Autre désignation: MUC1 (MUC1 Produits)

Synonymes: CA 15-3 Protein, CD227 Protein, EMA Protein, H23AG Protein, KL-6 Protein, MAM6 Protein, MCKD1 Protein, MUC-1 Protein, MUC-1/SEC Protein, MUC-1/X Protein, MUC1/ZD Protein, PEM Protein, PEMT Protein, PUM Protein, Muc-1 Protein, mucin 1, cell surface associated Protein, mucin 1, transmembrane Protein, MUC1 Protein, Muc1 Protein

Sujet: MUC1, the transmembrane glycoprotein Mucin 1, is usually found to be overexpressed in a variety of epithelial cancers playing an important role in disease progression. MUC1 isoforms such as MUC1/Y, which lacks the entire variable number of tandem repeat region, are involved in oncogenic processes by enhancing tumour initiation. MUC1/Y is therefore considered a promising target for the identification and treatment of epithelial cancers.

Poids moléculaire: 41.38 kDa. Due to glycosylation, the protein migrates to 55-65 kDa based on Tris-Bis PAGE result.

Pathways: Negative Regulation of intrinsic apoptotic Signaling