PD-1 Protein (AA 25-167) (Fc Tag,Biotin)
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- Antigène Voir toutes PD-1 (PDCD1) Protéines
- PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))
- Type de proteíne
- Recombinant
- Attributs du protein
- AA 25-167
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Origine
- Souris
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette PD-1 protéine est marqué à la Fc Tag,Biotin.
- Fonction
- Biotinylated Mouse PD-1/PDCD1 Protein (Primary Amine Labeling)
- Séquence
- Leu25-Gln167
- Attributs du produit
- Recombinant Biotinylated Mouse PD-1/PDCD1 Protein (Primary Amine Labeling) is expressed from HEK293 with hFc tag at the C-Terminus.It contains Leu25-Gln167.
- Pureté
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Stérilité
- 0.22 μm filtered
- niveau d'endotoxine
- Less than 1EU per μg by the LAL method.
- Biological Activity Comment
- The affinity constant of 1.32 μM as determined in SPR assay (Biacore T200). See testing image for detail.
- Top Product
- Discover our top product PDCD1 Protéine
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- PD-1 (PDCD1) (Programmed Cell Death 1 (PDCD1))
- Autre désignation
- PD-1 (PDCD1 Produits)
- Synonymes
- CD279 Protein, PD-1 Protein, PD1 Protein, SLEB2 Protein, hPD-1 Protein, hPD-l Protein, Ly101 Protein, Pdc1 Protein, programmed cell death 1 Protein, PDCD1 Protein, Pdcd1 Protein
- Sujet
- Programmed cell death protein 1, also known as PD-1 and CD279 , is a protein found on the surface of cells that has a role in regulating the immune system's response to the cells of the human body by down-regulating the immune system and promoting self tolerance by suppressing T cell inflammatory activity.
- Poids moléculaire
- 42.9 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Tris-Bis PAGE result.
- NCBI Accession
- NP_032824
- Pathways
- Cancer Immune Checkpoints
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