PILRA Protein (AA 20-197) (Fc Tag)

N° du produit ABIN7275474

Détail du produit

Antigène: PILRA (Paired Immunoglobin-Like Type 2 Receptor alpha (PILRA))

Type de proteíne: Recombinant

Attributs du protein: AA 20-197

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette PILRA protéine est marqué à la Fc Tag.

Fonction: Human PILRA Protein

Séquence: Gln20-Ala197

Attributs du produit: Recombinant Human PILRA Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Gln20-Ala197.

Pureté: > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Stérilité: 0.22 μm filtered

niveau d'endotoxine: Less than 1EU per μg by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Stock: -20 °C,-80 °C

Stockage commentaire: -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Date de péremption: 12 months

Détail du antigène

Antigène: PILRA (Paired Immunoglobin-Like Type 2 Receptor alpha (PILRA))

Autre désignation: PILRA (PILRA Produits)

Synonymes: PILRA Protein, FDF03 Protein, AV021745 Protein, RGD1562847 Protein, paired immunoglobin like type 2 receptor alpha Protein, paired immunoglobulin-like type 2 receptor alpha Protein, paired immunoglobin-like type 2 receptor alpha Protein, PILRA Protein, LOC489841 Protein, Pilra Protein

Sujet: Alzheimer's disease (AD) is a neurodegenerative disease characterized by a progressive decline in cognitive performance, Mild Cognitive Impairment (MCI) is instead an objective decline in cognitive performance that does not reach pathology. Paired immunoglobulin-like type 2 receptor alpha (PILRA) is a cell surface inhibitory receptor that was recently suggested to be involved in AD pathogenesis. In particular, the arginine-to-glycine substitution in position 78 (R78, rs1859788) was shown to be protective against AD.

Poids moléculaire: 47 kDa. Due to glycosylation, the protein migrates to 60-68 kDa based on Tris-Bis PAGE result.