Crystallography grade
PILRA
Origine: Souris
Hôte: Cellules d'insectes
Recombinant
>95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot.
ELISA, WB, Crys, SDS
Restrictions
For Research Use only
Format
Lyophilized
Reconstitution
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
Buffer
Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
Stock
-20 °C,-80 °C
Stockage commentaire
-20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Date de péremption
12 months
Antigène
PILRA
(Paired Immunoglobin-Like Type 2 Receptor alpha (PILRA))
PILRA Protein, FDF03 Protein, AV021745 Protein, RGD1562847 Protein, paired immunoglobin like type 2 receptor alpha Protein, paired immunoglobulin-like type 2 receptor alpha Protein, paired immunoglobin-like type 2 receptor alpha Protein, PILRA Protein, LOC489841 Protein, Pilra Protein
Sujet
Alzheimer's disease (AD) is a neurodegenerative disease characterized by a progressive decline in cognitive performance, Mild Cognitive Impairment (MCI) is instead an objective decline in cognitive performance that does not reach pathology. Paired immunoglobulin-like type 2 receptor alpha (PILRA) is a cell surface inhibitory receptor that was recently suggested to be involved in AD pathogenesis. In particular, the arginine-to-glycine substitution in position 78 (R78, rs1859788) was shown to be protective against AD.
Poids moléculaire
19.71 kDa. Due to glycosylation, the protein migrates to 43-60 kDa based on Tris-Bis PAGE result.