WFDC1 Protein (AA 32-192) (His tag)

N° du produit ABIN7275482

Détail du produit

Antigène: WFDC1 (WAP Four-Disulfide Core Domain 1 (WFDC1))

Type de proteíne: Recombinant

Attributs du protein: AA 32-192

Origine: Cynomolgus

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette WFDC1 protéine est marqué à la His tag.

Fonction: Cynomolgus PS20 Protein

Séquence: Lys32-Gln192

Attributs du produit: Recombinant Cynomolgus PS20 Protein is expressed from E.coli with His tag at the N-Terminus.It contains Lys32-Gln192.

Pureté: > 95 % as determined by Tris-Bis PAGE

Stérilité: 0.22 μm filtered

niveau d'endotoxine: Less than 1EU per μg by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Supplied as 0.22μm filtered solution in 20 mM PB, 500 mM NaCl ( pH 7.4).

Stock: -80 °C

Stockage commentaire: Valid for 12 months from date of receipt when stored at -80°C.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Date de péremption: 12 months

Détail du antigène

Antigène: WFDC1 (WAP Four-Disulfide Core Domain 1 (WFDC1))

Autre désignation: PS20 (WFDC1 Produits)

Synonymes: WFDC1 Protein, zgc:158671 Protein, PS20 Protein, 2310058A03Rik Protein, ps20 Protein, WAP four-disulfide core domain 1 Protein, WFDC1 Protein, wfdc1 Protein, Wfdc1 Protein

Sujet: The whey acidic protein family member, WFDC1/ps20 is a permissivity factor in HIV infection. Herein we describe a contrasting role for ps20 in limiting MHV-1 infection. Intranasal MHV-1 infection produces a respiratory infection in mice. Using ps20 knockout mice we provide evidence that intranasal MHV-1 infection results in increased lung viral titers in ps20(-/-) compared to ps20(/) mice. Roles for ps20 in regulating expression of neutrophil-specific chemotactic factors, thereby potentially modulating neutrophil migration, and in modulating neutrophil susceptibility to MHV-1 infection.

Poids moléculaire: 18.77 kDa. The protein migrates to 25-28 kDa based on Tris-Bis PAGE result.

NCBI Accession: XP_015298715