WFDC1 Protein (AA 24-211) (His tag)
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- Antigène Voir toutes WFDC1 Protéines
- WFDC1 (WAP Four-Disulfide Core Domain 1 (WFDC1))
- Type de proteíne
- Recombinant
- Attributs du protein
- AA 24-211
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Origine
- Souris
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Source
- Escherichia coli (E. coli)
- Purification/Conjugué
- Cette WFDC1 protéine est marqué à la His tag.
- Fonction
- Mouse PS20 Protein
- Séquence
- Gln24-Pro211
- Attributs du produit
- Recombinant Mouse PS20 Protein is expressed from E.coli with His tag at the N-Terminus.It contains Gln24-Pro211.
- Pureté
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Stérilité
- 0.22 μm filtered
- niveau d'endotoxine
- Less than 1EU per μg by the LAL method.
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- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Supplied as 0.22μm filtered solution in PBS ( pH 7.4).
- Stock
- -80 °C
- Stockage commentaire
- Valid for 12 months from date of receipt when stored at -80°C., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- WFDC1 (WAP Four-Disulfide Core Domain 1 (WFDC1))
- Autre désignation
- PS20 (WFDC1 Produits)
- Synonymes
- WFDC1 Protein, zgc:158671 Protein, PS20 Protein, 2310058A03Rik Protein, ps20 Protein, WAP four-disulfide core domain 1 Protein, WFDC1 Protein, wfdc1 Protein, Wfdc1 Protein
- Sujet
- The whey acidic protein family member, WFDC1/ps20 is a permissivity factor in HIV infection. Herein we describe a contrasting role for ps20 in limiting MHV-1 infection. Intranasal MHV-1 infection produces a respiratory infection in mice. Using ps20 knockout mice we provide evidence that intranasal MHV-1 infection results in increased lung viral titers in ps20(-/-) compared to ps20(/) mice. Roles for ps20 in regulating expression of neutrophil-specific chemotactic factors, thereby potentially modulating neutrophil migration, and in modulating neutrophil susceptibility to MHV-1 infection.
- Poids moléculaire
- 21.9 kDa. The protein migrates to 27-30 kDa based on Tris-Bis PAGE result.
- UniProt
- Q9ESH5
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