RAGE Protein (AA 23-340) (His tag)
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- Antigène Voir toutes RAGE (AGER) Protéines
- RAGE (AGER) (Advanced Glycosylation End Product-Specific Receptor (AGER))
- Type de proteíne
- Recombinant
- Attributs du protein
- AA 23-340
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Origine
- Souris
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette RAGE protéine est marqué à la His tag.
- Fonction
- Mouse AGER Protein
- Séquence
- Gly23-Ala340
- Attributs du produit
- Recombinant Mouse AGER Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Gly23-Ala340.
- Pureté
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Stérilité
- 0.22 μm filtered
- niveau d'endotoxine
- Less than 1EU per μg by the LAL method.
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- RAGE (AGER) (Advanced Glycosylation End Product-Specific Receptor (AGER))
- Autre désignation
- RAGE (AGER Produits)
- Synonymes
- RAGE Protein, AGER Protein, advanced glycosylation end-product specific receptor Protein, advanced glycosylation end product-specific receptor Protein, MAPK/MAK/MRK overlapping kinase Protein, AGER Protein, Ager Protein, LOC719012 Protein
- Sujet
- The receptor for advanced glycation end-products (RAGE) is a cell surface transmembrane multiligand receptor, encoded by the AGER gene. RAGE presents many transcripts, is expressed mainly in the lung, and involves multiple pathways (such as NFκB, Akt, p38, and MAP kinases) that initiate and perpetuate an unfavorable proinflammatory state.
- Poids moléculaire
- 34.85 kDa. Due to glycosylation, the protein migrates to 45-50 kDa based on Tris-Bis PAGE result.
- NCBI Accession
- NP_031451
- Pathways
- Carbohydrate Homeostasis, Toll-Like Receptors Cascades, Smooth Muscle Cell Migration, S100 Proteins
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