TGFBR2
(Transforming Growth Factor, beta Receptor II (70/80kDa) (TGFBR2))
Type de proteíne
Recombinant
Attributs du protein
AA 24-159
Origine
Humain
Source
HEK-293 Cells
Purification/Conjugué
Cette TGFBR2 protéine est marqué à la mFc-Avi Tag.
Fonction
Human TGF-beta RII/TGFBR2 Protein
Séquence
Ile24-Asp159
Attributs du produit
Recombinant Human TGF-beta RII/TGFBR2 Protein is expressed from HEK293 with mFc (IgG1) tag and Avi tag at C-Terminus.It contains Ile24-Asp159.
Pureté
> 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
Stérilité
0.22 μm filtered
niveau d'endotoxine
Less than 1EU per μg by the LAL method.
Biological Activity Comment
Immobilized Human Mature TGF beta 1, No Tag at 0.5μg/ml (100μl/well) on the plate. Dose response curve for Human TGF-beta RII, mFc Tag with the EC50 of 8ng/ml determined by ELISA. See testing image for detail.
TGFBR2
Origine: Humain
Hôte: HEK-293 Cells
Recombinant
>90 % as determined by SDS-PAGE.
Active
Restrictions
For Research Use only
Format
Lyophilized
Reconstitution
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
Buffer
Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
Stock
-20 °C,-80 °C
Stockage commentaire
-20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Date de péremption
12 months
Antigène
TGFBR2
(Transforming Growth Factor, beta Receptor II (70/80kDa) (TGFBR2))
The TGFBR2 gene provides instructions for making a protein called transforming growth factor-beta (TGF-β) receptor type 2. This receptor transmits signals from the cell surface into the cell through a process called signal transduction. Through this type of signaling, the environment outside the cell affects activities inside the cell such as stimulation of cell growth and division.
Poids moléculaire
44 kDa. Due to glycosylation, the protein migrates to 55-70 kDa based on Tris-Bis PAGE result.