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TLR3 Protein (AA 25-705) (His tag)

TLR3 Origine: Souris Hôte: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
N° du produit ABIN7275748
  • Antigène Voir toutes TLR3 Protéines
    TLR3 (Toll-Like Receptor 3 (TLR3))
    Type de proteíne
    Recombinant
    Attributs du protein
    AA 25-705
    Origine
    • 12
    • 8
    • 2
    • 1
    Souris
    Source
    • 8
    • 7
    • 4
    • 2
    HEK-293 Cells
    Purification/Conjugué
    Cette TLR3 protéine est marqué à la His tag.
    Fonction
    Mouse TLR3 Protein
    Séquence
    Thr25-Leu705
    Attributs du produit
    Recombinant Mouse TLR3 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Thr25-Leu705.
    Pureté
    > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
    Stérilité
    0.22 μm filtered
    niveau d'endotoxine
    Less than 1EU per μg by the LAL method.
    Top Product
    Discover our top product TLR3 Protéine
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    Buffer
    Lyophilized from 0.22μm filtered solution in PBS ( pH 8.0). Normally 8 % trehalose is added as protectant before lyophilization.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    TLR3 (Toll-Like Receptor 3 (TLR3))
    Autre désignation
    TLR3 (TLR3 Produits)
    Synonymes
    CD283 Protein, IIAE2 Protein, AI957183 Protein, zgc:123006 Protein, toll like receptor 3 Protein, toll-like receptor 3 Protein, TLR3 Protein, Tlr3 Protein, tlr3 Protein
    Sujet
    TLR3 is expressed in the central nervous system (CNS), where it is required to control HSV-1, which spreads from the epithelium to the CNS via cranial nerves. TLR3 is also expressed in epithelial and dendritic cells, which apparently use TLR3-independent pathways to prevent further dissemination of HSV-1 and to provide resistance to other pathogens in TLR3-deficient patients. Human TLR3 appears to be redundant in host defense to most microbes but is vital for natural immunity to HSV-1 in the CNS, which suggests that neurotropic viruses have contributed to the evolutionary maintenance of TLR3.
    Poids moléculaire
    78.6 kDa. Due to glycosylation, the protein migrates to 85-110 kDa based on Tris-Bis PAGE result.
    UniProt
    Q99MB1
    Pathways
    Signalisation TLR, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades
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