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Thyroperoxidase Protein (AA 19-846) (His tag)

TPO Origine: Humain Hôte: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
N° du produit ABIN7275771
  • Antigène Voir toutes Thyroperoxidase (TPO) Protéines
    Thyroperoxidase (TPO) (Thyroid Peroxidase (TPO))
    Type de proteíne
    Recombinant
    Attributs du protein
    AA 19-846
    Origine
    • 8
    • 6
    • 2
    Humain
    Source
    • 6
    • 5
    • 2
    • 2
    • 1
    HEK-293 Cells
    Purification/Conjugué
    Cette Thyroperoxidase protéine est marqué à la His tag.
    Fonction
    Human Thyroid Peroxidase Protein
    Séquence
    Phe19-Arg846
    Attributs du produit
    Recombinant Human Thyroid Peroxidase Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Phe19-Arg846.
    Pureté
    > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
    Stérilité
    0.22 μm filtered
    niveau d'endotoxine
    Less than 1EU per μg by the LAL method.
    Top Product
    Discover our top product TPO Protéine
  • Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Supplied as 0.22μm filtered solution in 20 mM Tris, 500 mM NaCl, 10 % Glycerol ( pH 7.4).
    Stock
    -80 °C
    Stockage commentaire
    Valid for 12 months from date of receipt when stored at -80°C., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    Thyroperoxidase (TPO) (Thyroid Peroxidase (TPO))
    Autre désignation
    Thyroid Peroxidase (TPO Produits)
    Synonymes
    MSA Protein, TDH2A Protein, TPX Protein, TPO Protein, msa Protein, tpx Protein, xtpo Protein, LOC100218312 Protein, thyroid peroxidase Protein, TPO Protein, Tpo Protein, tpo Protein, LOC100547103 Protein
    Sujet
    Thyroid peroxidase, also called thyroperoxidase (TPO) or iodide peroxidase that encodes a 933 amino-acid residue (aa) molecule with a single membrane-spanning region. Thyroid peroxidase plays a key role in thyroid hormone synthesis by catalyzing both the iodination of tyrosine residues to form monoiodotyrosine (MIT) and diiodotyrosine (DIT) residues and the coupling of iodotyrosine residues in Tg, resulting in the formation of T3 and T4. It is a frequent epitope of autoantibodies in autoimmune thyroid disease, for example, the expression of thyroid peroxidase is lost in papillary thyroid carcinoma.
    Poids moléculaire
    90.6 kDa. Due to glycosylation, the protein migrates to 95-105 kDa based on Tris-Bis PAGE result.
    Pathways
    Thyroid Hormone Synthesis
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