VLDLR Protein (AA 28-797) (His tag)

N° du produit ABIN7275822

Détail du produit

Antigène: VLDLR (Very Low Density Lipoprotein Receptor (VLDLR))

Type de proteíne: Recombinant

Attributs du protein: AA 28-797

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette VLDLR protéine est marqué à la His tag.

Fonction: Human VLDLR Protein

Séquence: Gly28-Ser797

Attributs du produit: Recombinant Human VLDLR Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Gly28-Ser797.

Pureté: > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Stérilité: 0.22 μm filtered

niveau d'endotoxine: Less than 1EU per μg by the LAL method.

Biological Activity Comment: The affinity constant of 9.78 μM as determined in SPR assay (Biacore T200). See testing image for detail.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Stock: -20 °C,-80 °C

Stockage commentaire: -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Date de péremption: 12 months

Détail du antigène

Antigène: VLDLR (Very Low Density Lipoprotein Receptor (VLDLR))

Autre désignation: VLDLR (VLDLR Produits)

Synonymes: CARMQ1 Protein, CHRMQ1 Protein, VLDLRCH Protein, AA408956 Protein, AI451093 Protein, AW047288 Protein, vldlr Protein, very low density lipoprotein receptor Protein, very low density lipoprotein receptor S homeolog Protein, VLDLR Protein, Vldlr Protein, vldlr.S Protein

Sujet: VLDLR cerebellar hypoplasia (VLDLR-CH) is characterized by non-progressive congenital ataxia that is predominantly truncal and results in delayed ambulation, moderate-to-profound intellectual disability, dysarthria, strabismus, and seizures.VLDLR-CH is inherited in an autosomal recessive manner. Carrier testing for at-risk relatives, prenatal testing for a pregnancy at increased risk and preimplantation genetic testing are possible when the pathogenic variants in a family are known.

Poids moléculaire: 85.9 kDa. Due to glycosylation, the protein migrates to 115-125 kDa based on Tris-Bis PAGE result.

Pathways: Cellular Response to Molecule of Bacterial Origin