CD4 Protein (CD4) (Biotin,His-Avi Tag)

N° du produit ABIN7316799

Protéine Recombinant CD4 exprimée dans HEK-293 Cells.

Aperçu rapide pour CD4 Protein (CD4) (Biotin,His-Avi Tag) (ABIN7316799)

Antigène: CD4

Type de proteíne: Recombinant

Origine: Macaque rhésus

Source: HEK-293 Cells

Pureté: 95,00 %

Classe de qualité: MALS verified

Détail du produit

Purification/Conjugué: Cette CD4 protéine est marqué à la Biotin,His-Avi Tag.

Fonction: Biotinylated Rhesus macaque CD4 Protein, His,Avitag™ (MALS verified)

Séquence: Lys 26 - Trp 390

Attributs du produit: Biotinylated Rhesus macaque CD4,His,Avitag is expressed from human 293 cells (HEK293). It contains AA Lys 26 - Trp 390 (Accession # G7N5T8-1).

niveau d'endotoxine: 1.0 EU per μg

Information d'application

Commentaires:

This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™). The protein has a calculated MW of 44.0 kDa. The protein migrates as 52-58 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: PBS, pH 7.4

Stock: -20 °C

Stockage commentaire: -20°C

Détail du antigène

Antigène: CD4

Autre désignation: CD4

Sujet: Synonyms:CD4,CD4mut,LEU3,Description:T-cell surface glycoprotein CD4 is also known as T-cell surface antigen T4/Leu-3. CD4 contains three Ig-like C2-type (immunoglobulin-like) domains and one Ig-like V-type (immunoglobulin-like) domain. CD4 is accessory protein for MHC class-II antigen/T-cell receptor interaction. CD4 induces the aggregation of lipid rafts. CD4 is a primary receptor used by HIV-1 to gain entry into host T cells. HIV infection leads to a progressive reduction of the number of T cells possessing CD4 receptors. Therefore, medical professionals refer to the CD4 count to decide when to begin treatment for HIV-infected patients.

Poids moléculaire: 44.0 kDa

Pathways: TCR Signaling, Maintenance of Protein Location, CXCR4-mediated Signaling Events