SARS-CoV-2 Spike S2 Protein (BA.1 - Omicron) (Biotin,His-Avi Tag)

N° du produit ABIN7447846

Détail du produit

Antigène: SARS-CoV-2 Spike S2

Type de proteíne: Recombinant

Attributs du protein: BA.1 - Omicron

Origine: SARS Coronavirus-2 (SARS-CoV-2), SARS CoV-2 Omicron

Source: HEK-293 Cells

Purification/Conjugué: Cette SARS-CoV-2 Spike S2 protéine est marqué à la Biotin,His-Avi Tag.

Fonction: Biotinylated SARS-CoV-2 Spike S2 protein, His,Avitag™ (BA.1/Omicron)

Séquence: Ser 686 - Pro 1213

Attributs du produit: Biotinylated SARS-CoV-2 Spike S2 protein, His,Avitag™ (BA.1/Omicron) is expressed from human 293 cells (HEK293). It contains AA Ser Ser 686 - Pro 1213 (Accession # QHD43416.1 (N764K, D796Y, N856K, Q954H, N969K, L981F, F817P, A892P, A899P, A942P, K986P, V987P). The mutations are identified on the SARS-CoV-2 Omicron variant (Pango lineage: BA.1, GISAID clade: GRA, Nextstrain clade: 21K). Proline substitutions (F817P, A892P, A899P, A942P, K986P, V987P) are introduced to prevent the formation of aggregates in the course of protein production.

Pureté: 95,00 %

niveau d'endotoxine: 1.0 EU per μg

Information d'application

Commentaires:

This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™). The protein has a calculated MW of 61.7 kDa. The protein migrates as 80-100 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: PBS, pH 7.4

Stock: -20 °C

Stockage commentaire: -20°C

Détail du antigène

Antigène: SARS-CoV-2 Spike S2

Autre désignation: SARS-CoV-2 Spike S2 protein (SARS-CoV-2 Spike S2 Produits)

Synonymes: E2 Protein, Surface Glycoprotein Protein, S Protein

Classe de substances: Viral Protein

Sujet: Synonyms:Spike,S2 protein,Spike glycoprotein Subunit2,S glycoprotein Subunit2,Spike protein S2,Description:It's been reported that SARS-CoV-2 can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.

Poids moléculaire: 61.7 kDa