GBA Protein (AA 40-536) (His tag)

N° du produit ABIN7454125

Détail du produit

Antigène: GBA (Glucosidase, Beta, Acid (GBA))

Type de proteíne: Recombinant

Attributs du protein: AA 40-536

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette GBA protéine est marqué à la His tag.

Fonction: Human GBA/glucocerebrosidase Protein

Séquence: Ala40-Gln536

Attributs du produit: Recombinant Human GBA/glucocerebrosidase Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ala40-Gln536.

Pureté: > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Stérilité: 0.22 μm filtered

niveau d'endotoxine: Less than 1EU per μg by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Stock: -20 °C,-80 °C

Stockage commentaire: -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Date de péremption: 12 months

Détail du antigène

Antigène: GBA (Glucosidase, Beta, Acid (GBA))

Autre désignation: GBA (GBA Produits)

Synonymes: GBA1 Protein, GCB Protein, GLUC Protein, BETA-GLUCOSIDASE Protein, T12J13.8 Protein, T12J13_8 Protein, beta glucosidase 25 Protein, PSPTO3318 Protein, PSPTO4290 Protein, GC Protein, GCase Protein, betaGC Protein, glucosylceramidase beta Protein, beta glucosidase 25 Protein, beta-glucosidase Protein, Beta-glucosidase Protein, glucosidase, beta, acid Protein, glucosylceramidase Protein, bglX-2 Protein, GBA Protein, BGLU25 Protein, PSPTO_3318 Protein, bglX Protein, bglA4 Protein, Gba Protein, LOC100399524 Protein, bglA.2 Protein, bglX-2 Protein

Sujet: Glucocerebrosidase (GBA) mutations are the most important genetic risk factor for the development of Parkinson disease (PD). GBA encodes the lysosomal enzyme glucocerebrosidase (GCase).

Poids moléculaire: 56.69 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Tris-Bis PAGE result.

NCBI Accession: NP_000148

Pathways: Cellular Glucan Metabolic Process