HLA-A*24:02 (Tetramer) protein (Survivin 2B)
Origine: Humain
Hôte: HEK-293 Cells
Recombinant
> 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
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- Antigène
- HLA-A*24:02
- Type de proteíne
- Recombinant
- Attributs du protein
- Tetramer
- Origine
- Humain
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Source
- HEK-293 Cells
- Purification/Conjugué
- Survivin 2B
- Fonction
- Human HLA-A*24:02 & B2M & Survivin 2B (AYACNTSTL) Tetramer Protein
- Séquence
- Gly25-Thr305 (HLA-A*24:02), Ile21-Met119 (B2M) and AYACNTSTL peptide
- Specificité
- Uni-Prot: AAA59600.1 (HLA-A*24:02), P61769 (B2M), AYACNTSTL
- Attributs du produit
- Recombinant Human Survivin 2B(HLA-A*24:02) Tetramer Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus,tetramer is assembled by biotinylated monomer and streptavidin.It contains Gly25-Thr305(HLA-A*24:02), Ile21-Met119(B2M) and AYACNTSTL peptide.
- Pureté
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Stérilité
- 0.22 μm filtered
- niveau d'endotoxine
- Less than 1EU per μg by the LAL method.
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Date de péremption
- 12 months
-
- Antigène
- HLA-A*24:02
- Sujet
- Survivin-2B, a known splice variant of survivin, has been reported to promote cell death in some cancer cells, although it keeps prosurvival function in others.survivin-2B promoted autophagy and further regulated cell death by accumulating and stabilizing IKK alpha in the nucleus.
- Poids moléculaire
- 258 kDa. Due to glycosylation, the protein migrates to 260-265 kDa under Non reducing (N) condition based on Tris-Bis PAGE result.
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