GPR75 Protéine

N° du produit ABIN7491667

Détail du produit

Antigène: GPR75 (G Protein-Coupled Receptor 75 (GPR75))

Type de proteíne: Synthetic

Origine: Humain

Source: HEK-293 Cells

Fonction: Human GPR75 full length protein-synthetic nanodisc

Attributs du produit: Full Length Transmembrane Proteins (synthetic Nanodisc)

Information d'application

Indications d'application:

• Applications for VLPs:
• ELISA
• SPR affinity analysis
• Phage display screening
• Immunization
• Cell based assays
• CAR-T cell screening
• Protein cystal structure analysis

Commentaires:

Synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Supplied in nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0)

Stock: -20 °C,-80 °C

Stockage commentaire: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Date de péremption: 12 months

Détail du antigène

Antigène: GPR75 (G Protein-Coupled Receptor 75 (GPR75))

Autre désignation: GPR75 (GPR75 Produits)

Synonymes: GPR75 Protein, GPRchr2 Protein, WI31133 Protein, G protein-coupled receptor 75 Protein, G protein-coupled receptor 75 S homeolog Protein, GPR75 Protein, gpr75 Protein, Gpr75 Protein, gpr75.S Protein

Sujet: GPRchr2,
Description: WI31133G protein-coupled receptor that is activated by the chemokine CCL5/RANTES. Probably coupled to heterotrimeric Gq proteins, it stimulates inositol trisphosphate production and calcium mobilization upon activation. Together with CCL5/RANTES, may play a role in neuron survival through activation of a downstream signaling pathway involving the PI3, Akt and MAP kinases. CCL5/RANTES may also regulate insulin secretion by pancreatic islet cells through activation of this receptor.

Poids moléculaire: The human full length GPR75 protein has a MW of 59.4 kDa

UniProt: O95800