GPR77 Protéine

N° du produit ABIN7491551

Détail du produit

Antigène: GPR77 (G Protein-Coupled Receptor 77 (GPR77))

Type de proteíne: Synthetic

Origine: Humain

Source: HEK-293 Cells

Fonction: Human C5AR2 full length protein-synthetic nanodisc

Attributs du produit: Full Length Transmembrane Proteins (synthetic Nanodisc)

Information d'application

Indications d'application:

• Applications for VLPs:
• ELISA
• SPR affinity analysis
• Phage display screening
• Immunization
• Cell based assays
• CAR-T cell screening
• Protein cystal structure analysis

Commentaires:

Synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Supplied in nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0)

Stock: -20 °C,-80 °C

Stockage commentaire: Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.

Date de péremption: 12 months

Détail du antigène

Antigène: GPR77 (G Protein-Coupled Receptor 77 (GPR77))

Autre désignation: C5AR2 (GPR77 Produits)

Synonymes: GPR77 Protein, C5L2 Protein, GPF77 Protein, E030029A11Rik Protein, Gpr77 Protein, complement component 5a receptor 2 Protein, C5AR2 Protein, C5ar2 Protein

Sujet: C5L2, GPF77, GPR77
Description: This gene encodes a G-protein coupled receptor 1 family member involved in the complement system of the innate immune response. Unlike classical G-protein coupled receptors, the encoded protein does not associate with intracellular G-proteins. It may instead modulate signal transduction through the beta-arrestin pathway, and may alternatively act as a decoy receptor. This gene may be involved in coronary artery disease and in the pathogenesis of sepsis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2012]

Poids moléculaire: The human full length C5AR2 protein has a MW of 36.1 kDa

UniProt: Q9P296