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HHLA2 Protein (Biotin,His-Avi Tag)

HHLA2 Origine: Cynomolgus Hôte: HEK-293 Cells Recombinant 90 %
N° du produit ABIN7488771
  • Antigène Voir toutes HHLA2 Protéines
    HHLA2 (HERV-H LTR-Associating 2 (HHLA2))
    Type de proteíne
    Recombinant
    Origine
    • 8
    • 1
    Cynomolgus
    Source
    • 7
    • 1
    • 1
    HEK-293 Cells
    Purification/Conjugué
    Cette HHLA2 protéine est marqué à la Biotin,His-Avi Tag.
    Fonction
    Biotinylated Cynomolgus B7-H7 / HHLA2 Protein, His,Avitag™
    Séquence
    Ile 21 - Asn 345
    Attributs du produit
    Biotinylated Cynomolgus B7-H7, His,Avitag is expressed from human 293 cells (HEK293). It contains AA Ile 21 - Asn 345 (Accession # XP_005548285.1).
    Pureté
    90 %
    niveau d'endotoxine
    1.0 EU per μg
    Top Product
    Discover our top product HHLA2 Protéine
  • Commentaires

    This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™). (Biotin,10xHis , Avi) The protein has a calculated MW of 39.1 kDa. The protein migrates as 66-80 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    PBS, pH 7.4
    Stock
    -20 °C
    Stockage commentaire
    -20°C
  • Antigène
    HHLA2 (HERV-H LTR-Associating 2 (HHLA2))
    Autre désignation
    B7-H7 (HHLA2 Produits)
    Synonymes
    B7H7 Protein, HERV-H LTR-associating 2 Protein, HHLA2 Protein, hhla2 Protein
    Sujet
    B7-H7 (HHLA2) is a newly identified B7 family member that regulates human T-cell functions. B7-H7 was previously known as human endogenous retrovirus-H long terminal repeat associating 2 (HHLA2) with unidentified function. Recently, B7-H7 has been identified as a specific ligand for human CD28H. The B7-H7-CD28H pathway strongly promoted CD4+ T-cell proliferation and cytokine production via an AKT-dependent signaling cascade in the presence of TCR signaling, suggesting B7-H7 comprises a new co-stimulatory pathway. The first IgV domain of B7-H7, which presumably binds to a putative receptor, shows the highest homology to other B7 family members.
    Poids moléculaire
    39.1 kDa
    NCBI Accession
    XP_005548285
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