CD3 epsilon Protein (CD3E) (His tag)
Aperçu rapide pour CD3 epsilon Protein (CD3E) (His tag) (ABIN7482405)
Antigène
Voir toutes CD3 epsilon (CD3E) ProtéinesType de proteíne
Origine
Source
Pureté
Classe de qualité
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Purification/Conjugué
- Cette CD3 epsilon protéine est marqué à la His tag.
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Fonction
- Canine CD3 epsilon Protein, His Tag (MALS verified)
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Séquence
- Gln 22 - Leu 122
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Attributs du produit
- Canine CD3 epsilon Protein, His Tag (MALS verified) is expressed from human 293 cells (HEK293). It contains AA Gln 22 - Leu 122 (Accession # P27597).
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niveau d'endotoxine
- 1.0 EU per μg
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CD3 epsilon (CD3E) (AA 22-117) protein (His tag)
CD3E Origine: Cynomolgus Hôte: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD3 epsilon (CD3E) (AA 23-48) protein (Fc-Avi Tag)CD3E Origine: Humain Hôte: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD3 epsilon (CD3E) (AA 22-48) protein (Fc-Avi Tag)CD3E Origine: Cynomolgus Hôte: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD3 epsilon (CD3E) (AA 23-48) protein (Fc-Avi Tag,Biotin)CD3E Origine: Humain Hôte: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD3 epsilon (CD3E) (AA 22-48) protein (Fc-Avi Tag,Biotin)CD3E Origine: Cynomolgus Hôte: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
CD3 epsilon (CD3E) (Active) protein (mFc Tag)CD3E Origine: Humain Hôte: Human Cells Recombinant >95 % as determined by reducing SDS-PAGE. Active
CD3 epsilon (CD3E) (AA 23-126) protein (His tag,AVI tag,Biotin)CD3E Origine: Humain Hôte: HEK-293 Cells Recombinant >90 % as determined by SDS-PAGE.
CD3 epsilon (CD3E) (AA 22-117) protein (Fc Tag)CD3E Origine: Cynomolgus Hôte: Mammalian Cells Recombinant The purity of the protein is greater than 95 % as determined by SDS-PAGE and Coomassie blue staining.
CD3 epsilon (CD3E) (AA 23-207) protein (GST tag)CD3E Origine: Humain Hôte: Wheat germ Recombinant WB, ELISA, AP, AA
CD3 epsilon (CD3E) proteinCD3E Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 90 % pure SDS
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Commentaires
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This protein carries a polyhistidine tag at the C-terminus. (10xHis) The protein has a calculated MW of 16.7 kDa. The protein migrates as 19-25 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Buffer
- PBS, pH 7.4
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Stock
- -20 °C
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Stockage commentaire
- -20°C
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- CD3 epsilon (CD3E)
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Autre désignation
- CD3 epsilon
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Sujet
- CD3e molecule, epsilon is also known as CD3E, is a T-cell surface single-pass type I membrane glycoprotein. CD3E contains 1 Ig-like (immunoglobulin-like) domain and 1 ITAM domain. CD3E, together with CD3-gamma, CD3-delta and CD3-zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. CD3E plays an essential role in T-cell development, and defects in CD3E gene cause severe immunodeficiency. CD3E gene has also been linked to a susceptibility to type I diabetes in women. CD3E has been shown to interact with TOP2B, CD3EAP and NCK2.
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Poids moléculaire
- 16.7 kDa
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Pathways
- TCR Signaling, CXCR4-mediated Signaling Events, Ubiquitin Proteasome Pathway
Antigène
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