CTXB Protein (His tag)
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- Antigène Tous les produits CTXB
- CTXB (CtxB Gene Product (CTXB))
- Type de proteíne
- Recombinant
- Origine
- Vibrio sp.
- Source
- HEK-293 Cells
- Purification/Conjugué
- Cette CTXB protéine est marqué à la His tag.
- Fonction
- Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961) Cholera enterotoxin subunit B Protein, His Tag (MALS verified)
- Séquence
- Thr 22 - Asn 124
- Attributs du produit
- Vibrio cholerae serotype O1 Cholera enterotoxin subunit B, His Tag is expressed from human 293 cells (HEK293). It contains AA Thr 22 - Asn 124 (Accession # P01556).
- Pureté
- 95 %
- niveau d'endotoxine
- 1.0 EU per μg
- Classe de qualité
- MALS verified
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- Commentaires
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This protein carries a polyhistidine tag at the C-terminus. (10xHis) The protein has a calculated MW of 13.5 kDa. The protein migrates as 16-17 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- PBS, pH 7.4
- Stock
- -20 °C
- Stockage commentaire
- -20°C
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- Antigène
- CTXB (CtxB Gene Product (CTXB))
- Autre désignation
- Cholera Enterotoxin Subunit B (CTXB Produits)
- Sujet
- Cholera toxin is protein complex secreted by the bacterium Vibrio cholerae. It is responsible for the massive, watery diarrhea characteristic of cholera infection. The B subunit of cholera toxin (CtxB) binds to a GM1-ganglioside receptor, a ubiquitous glycolipid cell surface receptor. This binding is widely accepted to initiate toxin action by triggering uptake and delivery of the toxin A subunit into cells. The beta chain has no toxic activity by itself. The holotoxin consists of a pentameric ring of B subunits whose central pore is occupied by the A subunit. The A subunit contains two chains, A1 and A2, linked by a disulfide bridge.
- Poids moléculaire
- 13.5 kDa
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