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CTXB Protein (His tag)

MALS verified CTXB Origine: Vibrio sp. Hôte: HEK-293 Cells Recombinant 95 %
N° du produit ABIN7482638
  • Antigène Tous les produits CTXB
    CTXB (CtxB Gene Product (CTXB))
    Type de proteíne
    Recombinant
    Origine
    Vibrio sp.
    Source
    HEK-293 Cells
    Purification/Conjugué
    Cette CTXB protéine est marqué à la His tag.
    Fonction
    Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961) Cholera enterotoxin subunit B Protein, His Tag (MALS verified)
    Séquence
    Thr 22 - Asn 124
    Attributs du produit
    Vibrio cholerae serotype O1 Cholera enterotoxin subunit B, His Tag is expressed from human 293 cells (HEK293). It contains AA Thr 22 - Asn 124 (Accession # P01556).
    Pureté
    95 %
    niveau d'endotoxine
    1.0 EU per μg
    Classe de qualité
    MALS verified
  • Commentaires

    This protein carries a polyhistidine tag at the C-terminus. (10xHis) The protein has a calculated MW of 13.5 kDa. The protein migrates as 16-17 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    PBS, pH 7.4
    Stock
    -20 °C
    Stockage commentaire
    -20°C
  • Antigène
    CTXB (CtxB Gene Product (CTXB))
    Autre désignation
    Cholera Enterotoxin Subunit B (CTXB Produits)
    Sujet
    Cholera toxin is protein complex secreted by the bacterium Vibrio cholerae. It is responsible for the massive, watery diarrhea characteristic of cholera infection. The B subunit of cholera toxin (CtxB) binds to a GM1-ganglioside receptor, a ubiquitous glycolipid cell surface receptor. This binding is widely accepted to initiate toxin action by triggering uptake and delivery of the toxin A subunit into cells. The beta chain has no toxic activity by itself. The holotoxin consists of a pentameric ring of B subunits whose central pore is occupied by the A subunit. The A subunit contains two chains, A1 and A2, linked by a disulfide bridge.
    Poids moléculaire
    13.5 kDa
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