LY9 Protein (AA 48-453) (His tag)

N° du produit ABIN7504257

Détail du produit

Antigène: LY9 (CD229) (Lymphocyte Antigen 9 (CD229))

Type de proteíne: Recombinant

Attributs du protein: AA 48-453

Origine: Souris

Source: HEK-293 Cells

Purification/Conjugué: Cette LY9 protéine est marqué à la His tag.

Fonction: Mouse CD229/SLAMF3 Protein

Séquence: Lys48-Arg453

Attributs du produit: Recombinant Mouse CD229/SLAMF3 Protein is expressed from HEK293 with His tag at the C-terminus.It contains Lys48-Arg453.

Pureté: > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Stérilité: 0.22 μm filtered

niveau d'endotoxine: Less than 1EU per μg by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22 μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Stock: -20 °C,-80 °C

Stockage commentaire: -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Date de péremption: 12 months

Détail du antigène

Antigène: LY9 (CD229) (Lymphocyte Antigen 9 (CD229))

Autre désignation: CD229 (CD229 Produits)

Synonymes: LY9 Protein, CD229 Protein, SLAMF3 Protein, hly9 Protein, mLY9 Protein, AI893573 Protein, Lgp100 Protein, Ly-9 Protein, T100 Protein, lymphocyte antigen 9 Protein, LY9 Protein, Ly9 Protein

Sujet: CD229 was strongly and homogeneously overexpressed on the PC of patients with monoclonal gammopathy of undetermined significance (MGUS), smoldering myeloma, MM, and PC leukemia. CD229 was particularly overexpressed on those PC showing an abnormal phenotype such as expression of CD56. Most importantly, CD229 was also highly expressed on those cells in the patients' BM displaying the phenotype of chemotherapy-resistant and myeloma-propagating cells.

Poids moléculaire: 46.19 kDa. Due to glycosylation, the protein migrates to 60-80 kDa based on Tris-Bis PAGE result.

UniProt: Q01965

Pathways: BCR Signaling