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C-Type Lectin Domain Family 4, Member M (CLEC4M) (AA 71-399) Protéine

CLEC4M Origine: Humain Hôte: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
N° du produit ABIN7504304
  • Antigène Voir toutes C-Type Lectin Domain Family 4, Member M (CLEC4M) Protéines
    C-Type Lectin Domain Family 4, Member M (CLEC4M)
    Type de proteíne
    Recombinant
    Attributs du protein
    AA 71-399
    Origine
    • 8
    • 1
    Humain
    Source
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    HEK-293 Cells
    Fonction
    Human CLEC4M/CD299 Protein
    Séquence
    Gln71-Glu399
    Attributs du produit
    Recombinant Human CLEC4M/CD299 Protein is expressed from HEK293 without tag.It contains Gln71-Glu399.
    Pureté
    > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
    Stérilité
    0.22 μm filtered
    niveau d'endotoxine
    Less than 1EU per μg by the LAL method.
    Top Product
    Discover our top product CLEC4M Protéine
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    Buffer
    Lyophilized from 0.22 μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    C-Type Lectin Domain Family 4, Member M (CLEC4M)
    Autre désignation
    CLEC4M (CLEC4M Produits)
    Synonymes
    CD209L Protein, CD299 Protein, DC-SIGN2 Protein, DC-SIGNR Protein, DCSIGNR Protein, HP10347 Protein, L-SIGN Protein, LSIGN Protein, CD209B Protein, C-type lectin domain family 4 member M Protein, CLEC4M Protein
    Sujet
    CLEC4M, also known as DC-SIGNR, L-SIGN or CD209L, is a Ca2+-dependent C-type lectin. CLEC4M and its homologue DC-SIGN are encoded by the closely related lectin gene cluster on chromosome 19p13.3. higher expression of CLEC4M is associated with poor clinical prognosis in lung cancer patients and enhances the resistance of NSCLC cells to cisplatin. Inhibition of CLEC4M expression significantly increased cisplatin sensitivity, suggesting potential clinical significance for targeting CLEC4M in overcoming cisplatin resistance.
    Poids moléculaire
    37.72 kDa. Due to glycosylation, the protein migrates to 38-50 kDa based on Tris-Bis PAGE result.
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