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HLA-A*02:01 (Monomer) protein (Biotin,MAGE-A3)

Origine: Humain Hôte: HEK-293 Cells Recombinant > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
N° du produit ABIN7504362
  • Antigène
    HLA-A*02:01
    Type de proteíne
    Recombinant
    Attributs du protein
    Monomer
    Origine
    • 70
    • 4
    Humain
    Source
    • 65
    • 4
    • 1
    HEK-293 Cells
    Purification/Conjugué
    Biotin,MAGE-A3
    Fonction
    Biotinylated Human HLA-A*02:01 & B2M & MAGE-A3 (KVAELVHFL) Monomer Protein
    Séquence
    Gly25-Thr305 (HLA-A*02:01), Ile21-Met119 (B2M) and KVAELVHFL peptide
    Specificité
    Uni-Prot: A0A140T913 (HLA-A*02:01), P61769 (B2M), KVAELVHFL
    Attributs du produit
    Recombinant Biotinylated Human HLA-A*02:01 & B2M & MAGE-A3 (KVAELVHFL) Monomer Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Gly25-Thr305 (HLA-A*02:01), Ile21-Met119 (B2M) and KVAELVHFL peptide.
    Pureté
    > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
    Stérilité
    0.22 μm filtered
    niveau d'endotoxine
    Less than 1EU per μg by the LAL method.
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
    Buffer
    Lyophilized from 0.22 μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
    Stock
    -20 °C,-80 °C
    Stockage commentaire
    -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    HLA-A*02:01
    Sujet
    Melanoma antigen family A, 3 (MAGE-A3) is a cancer-testis antigen whose expression has been demonstrated in a wide array of malignancies including melanoma, brain, breast, lung and ovarian cancer. In addition, its ability to elicit spontaneous humoral and cellular immune responses has been shown in cancer patients.
    Poids moléculaire
    50.50 kDa. Due to glycosylation, the protein migrates to 50-65 kDa based on Tris-Bis PAGE result.
    UniProt
    A0A140T913
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