ITGAV/ITGB1 Protein (AA 31-992, Heterodimer) (His-Avi Tag)

N° du produit ABIN7504451

Détail du produit

Antigène: ITGAV/ITGB1 (Integrin alpha V + beta 1 (ITGAV/ITGB1))

Type de proteíne: Recombinant

Attributs du protein: AA 31-992, Heterodimer

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette ITGAV/ITGB1 protéine est marqué à la His-Avi Tag.

Fonction: Human Integrin alpha V beta 1 (ITGAV & ITGB1) Heterodimer Protein

Séquence: Phe31-Val992 (ITGAV) acidic tail & Gln21-Asp728 (ITGB1) basic tail

Specificité: Uni-Prot: P06756-1 (ITGAV), P05556-1 (ITGB1)

Attributs du produit: Recombinant Human Integrin alpha V beta 1 (ITGAV & ITGB1) Heterodimer Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Phe31-Val992 (ITGAV) acidic tail & Gln21-Asp728 (ITGB1) basic tail.

Pureté: > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Stérilité: 0.22 μm filtered

niveau d'endotoxine: Less than 1EU per μg by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22 μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Stock: -20 °C,-80 °C

Stockage commentaire: -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Date de péremption: 12 months

Détail du antigène

Antigène: ITGAV/ITGB1 (Integrin alpha V + beta 1 (ITGAV/ITGB1))

Autre désignation: Integrin alpha V beta 1 (ITGAV/ITGB1 Produits)

Sujet: Integrins are transmembrane heterodimeric receptors that contribute to diverse biological functions and play a conserved role in mediating cell adhesion to fixed extracellular ligands and in the maintenance of tissue integrity. αVβ1 is the major integrin on several different primary fibroblasts responsible for binding to TGFb1 LAP and for mediating activation of latent TGFb by these cells.

Poids moléculaire: 114 kDa (ITGAV) and 83.2 kDa (ITGB1). Due to glycosylation, the protein migrates to 130-160 kDa (ITGAV) and 100-120 kDa (ITGB1) based on Tris-Bis PAGE result.