ITCH Protein (AA 485-862)
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- Antigène Voir toutes ITCH Protéines
- ITCH (Itchy E3 Ubiquitin Protein Ligase Homolog (ITCH))
- Type de proteíne
- Recombinant
- Attributs du protein
- AA 485-862
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Origine
- Humain
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Source
- Escherichia coli (E. coli)
- Fonction
- Human ITCH Protein
- Séquence
- Arg485-Glu862
- Attributs du produit
- Recombinant Human ITCH Protein is expressed from E.coli without tag.It contains Arg485-Glu862.
- Pureté
- > 95 % as determined by Tris-Bis PAGE,> 90 % as determined by HPLC
- Stérilité
- 0.22 μm filtered
- niveau d'endotoxine
- Less than 1EU per μg by the LAL method.
- Top Product
- Discover our top product ITCH Protéine
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22 μm filtered solution in PBS, 200 mM L-Arginine ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- ITCH (Itchy E3 Ubiquitin Protein Ligase Homolog (ITCH))
- Autre désignation
- ITCH (ITCH Produits)
- Synonymes
- AIF4 Protein, AIP4 Protein, NAPP1 Protein, dJ468O1.1 Protein, 6720481N21Rik Protein, 8030492O04Rik Protein, A130065M08 Protein, C230047C07Rik Protein, itchy E3 ubiquitin protein ligase Protein, itchy, E3 ubiquitin protein ligase Protein, ITCH Protein, Itch Protein
- Sujet
- Itch or itchy E3 is a member of the homologous to E6-associated protein C-terminus (HECT)-type family of E3 ligases, with the protein-interacting WW-domains for the recruitment of substrate and the HECT domain for the transfer of ubiquitin to the substrate, and its deletion results in an itchy phenotype with constant skin scratching and multi-organ inflammation.
- Poids moléculaire
- 44.98 kDa same as Tris-Bis PAGE result.
- NCBI Accession
- NP_113671
- Pathways
- Activation of Innate immune Response, CXCR4-mediated Signaling Events
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