LY6G6D Protein (AA 20-104) (His tag)

N° du produit ABIN7504463

Détail du produit

Antigène: LY6G6D (Lymphocyte Antigen 6 Complex, Locus G6D (LY6G6D))

Type de proteíne: Recombinant

Attributs du protein: AA 20-104

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette LY6G6D protéine est marqué à la His tag.

Fonction: Human LY6G6D Protein

Séquence: Asn20-Ser104

Attributs du produit: Recombinant Human LY6G6D Protein is expressed from HEK293 with His tag at the C-terminus.It contains Asn20-Ser104.

Pureté: > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC

Stérilité: 0.22 μm filtered

niveau d'endotoxine: Less than 1EU per μg by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22 μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.

Stock: -20 °C,-80 °C

Stockage commentaire: -20 to -80°C for 12 months as supplied from date of receipt., -80°C for 3-6 months after reconstitution., 2-8°C for 2-7 days after reconstitution., Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Date de péremption: 12 months

Détail du antigène

Antigène: LY6G6D (Lymphocyte Antigen 6 Complex, Locus G6D (LY6G6D))

Autre désignation: LY6G6D (LY6G6D Produits)

Synonymes: C6orf23 Protein, G6D Protein, LY6-D Protein, MEGT1 Protein, NG25 Protein, A930024F17Rik Protein, G6d Protein, G6f Protein, NG32 Protein, Ly6-D Protein, Ng25 Protein, lymphocyte antigen 6 family member G6D Protein, lymphocyte antigen 6 complex, locus G6D Protein, LY6G6D Protein, Ly6g6d Protein

Sujet: LY6G6D is a selectively expressed colorectal cancer antigen that can be used for targeting a therapeutic T-cell response by a T-cell engager.LY6G6D was identified as a selectively expressed CRC antigen that can be utilized to potently re-direct and activate cytotoxic T-cells to lyse LY6G6D expressing CRC using a TcE. This effect can be spread to target negative neighboring tumor cells, potentially leading to improved therapeutic efficacy.

Poids moléculaire: 10.20 kDa. Due to glycosylation, the protein migrates to 13-15 kDa based on Tris-Bis PAGE result.

UniProt: O95868