LY6G6D Protein (AA 20-104) (Fc Tag)
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- Antigène Voir toutes LY6G6D Protéines
- LY6G6D (Lymphocyte Antigen 6 Complex, Locus G6D (LY6G6D))
- Type de proteíne
- Recombinant
- Attributs du protein
- AA 20-104
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Origine
- Humain
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette LY6G6D protéine est marqué à la Fc Tag.
- Fonction
- Human LY6G6D Protein
- Séquence
- Asn20-Ser104
- Attributs du produit
- Recombinant Human LY6G6D Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Asn20-Ser104.
- Pureté
- > 95 % as determined by Tris-Bis PAGE,> 95 % as determined by HPLC
- Stérilité
- 0.22 μm filtered
- niveau d'endotoxine
- Less than 1EU per μg by the LAL method.
- Top Product
- Discover our top product LY6G6D Protéine
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.
- Buffer
- Lyophilized from 0.22μm filtered solution in PBS ( pH 7.4). Normally 8 % trehalose is added as protectant before lyophilization.
- Stock
- -20 °C,-80 °C
- Stockage commentaire
- -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- LY6G6D (Lymphocyte Antigen 6 Complex, Locus G6D (LY6G6D))
- Autre désignation
- LY6G6D (LY6G6D Produits)
- Synonymes
- C6orf23 Protein, G6D Protein, LY6-D Protein, MEGT1 Protein, NG25 Protein, A930024F17Rik Protein, G6d Protein, G6f Protein, NG32 Protein, Ly6-D Protein, Ng25 Protein, lymphocyte antigen 6 family member G6D Protein, lymphocyte antigen 6 complex, locus G6D Protein, LY6G6D Protein, Ly6g6d Protein
- Sujet
- LY6G6D is a selectively expressed colorectal cancer antigen that can be used for targeting a therapeutic T-cell response by a T-cell engager.LY6G6D was identified as a selectively expressed CRC antigen that can be utilized to potently re-direct and activate cytotoxic T-cells to lyse LY6G6D expressing CRC using a TcE. This effect can be spread to target negative neighboring tumor cells, potentially leading to improved therapeutic efficacy.
- Poids moléculaire
- 35.87 kDa. Due to glycosylation, the protein migrates to 40-50 kDa based on Tris-Bis PAGE result.
- UniProt
- O95868
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