PKM2 Protein (AA 2-531) (His tag)

N° du produit ABIN7504510

Détail du produit

Antigène: PKM2 (Pyruvate Kinase M2 (PKM2))

Type de proteíne: Recombinant

Attributs du protein: AA 2-531

Origine: Souris

Source: Baculovirus infected Insect Cells

Purification/Conjugué: Cette PKM2 protéine est marqué à la His tag.

Fonction: Mouse PKM2 Protein

Séquence: Pro2-Pro531

Attributs du produit: Recombinant Mouse PKM2 Protein is expressed from Baculovirus-Insect Cells with His tag at the N-terminus.It contains Pro2-Pro531.

Pureté: > 95 % as determined by Tris-Bis PAGE

Stérilité: 0.22 μm filtered

niveau d'endotoxine: Less than 1EU per μg by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in distilled water.

Buffer: Lyophilized from 0.22μm filtered solution in 20 mM Tris, 500 mM NaCl ( pH 7.0). Normally 8 % trehalose is added as protectant before lyophilization.

Stock: -20 °C,-80 °C

Stockage commentaire: -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Date de péremption: 12 months

Détail du antigène

Antigène: PKM2 (Pyruvate Kinase M2 (PKM2))

Autre désignation: PKM2 (PKM2 Produits)

Synonymes: CTHBP Protein, OIP3 Protein, PK3 Protein, PKM2 Protein, TCB Protein, THBP1 Protein, AA414905 Protein, AL024370 Protein, AL024424 Protein, Pk-2 Protein, Pk-3 Protein, Pk3 Protein, Pkm2 Protein, PKM12 Protein, PKM Protein, pyruvate kinase M1/2 Protein, pyruvate kinase, muscle Protein, PKM Protein, Pkm Protein

Sujet: Pyruvate kinase M2 (PKM2), a key rate-limiting enzyme of glycolysis, is a critical regulator in tumor metabolism. PKM2 has been demonstrated to overexpressed in various cancers and promoted proliferation and metastasis of tumor cells.

Poids moléculaire: 58.95 kDa same as Tris-Bis PAGE result.

NCBI Accession: NP_001240812

Pathways: L'effet Warburg