PLAT Protein (AA 36-562) (His tag)

N° du produit ABIN7504551

Détail du produit

Antigène: PLAT (Plasminogen Activator, Tissue (PLAT))

Type de proteíne: Recombinant

Attributs du protein: AA 36-562

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette PLAT protéine est marqué à la His tag.

Fonction: Human tPA Protein

Séquence: Ser36-Pro562

Attributs du produit: Recombinant Human tPA Protein is expressed from HEK293 with His tag at the C-terminus.It contains Ser36-Pro562, which consists of two chains: chain A (Ser36-Arg310) and chain B (Ile311-Pro562).

Pureté: > 95 % as determined by Tris-Bis PAGE

Stérilité: 0.22 μm filtered

niveau d'endotoxine: Less than 1EU per μg by the LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/mL is recommended. Dissolve the lyophilized protein in 20 mM MES, 300 mM Nacl, 200 mM Arginine ( pH 5.5).

Buffer: Lyophilized from 0.22μm filtered solution in 20 mM MES, 300 mM Nacl, 200 mM Arginine ( pH 5.5). Normally 8 % trehalose is added as protectant before lyophilization.

Stock: -20 °C,-80 °C

Stockage commentaire: -20 to -80°C for 12 months as supplied from date of receipt.,-80°C for 3-6 months after reconstitution.,2-8°C for 2-7 days after reconstitution.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Date de péremption: 12 months

Détail du antigène

Antigène: PLAT (Plasminogen Activator, Tissue (PLAT))

Autre désignation: tPA (PLAT Produits)

Synonymes: T-PA Protein, TPA Protein, AU020998 Protein, AW212668 Protein, D8Ertd2e Protein, tPA Protein, PATISS Protein, tpa Protein, Plat Protein, plat Protein, t-pa Protein, plasminogen activator, tissue type Protein, plasminogen activator, tissue Protein, chromosome 20 open reading frame 181 Protein, plasminogen activator, tissue L homeolog Protein, PLAT Protein, Plat Protein, plat Protein, C20orf181 Protein, plat.L Protein

Sujet: Tissue plasminogen activator (tPA) is the predominant plasminogen activator present in the vascular and nervous systems.t tPA is not only neuroprotective for postnatal primary cortical neurons, but also that the predominant route for enhancing cell survival is via an mTORdependent mechanism.

Poids moléculaire: 60.13 kDa. The protein is activated by thermolysin and cleaved to a 2-chain protease, it migrates to 40-45 kDa (Chain A) and 35-40 kDa (Chain B) based on Tris-Bis PAGE result.

Pathways: Autophagy, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling, SARS-CoV-2 Protein Interactome