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MECP2 Protein (AA 1-177) (His tag)

MECP2 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant >95 % as determined by reducing SDS-PAGE.
N° du produit ABIN7505031
  • Antigène Voir toutes MECP2 Protéines
    MECP2 (Methyl CpG Binding Protein 2 (MECP2))
    Type de proteíne
    Recombinant
    Attributs du protein
    AA 1-177
    Origine
    • 8
    • 3
    • 2
    • 1
    Humain
    Source
    • 3
    • 2
    • 2
    • 2
    • 2
    Escherichia coli (E. coli)
    Purification/Conjugué
    Cette MECP2 protéine est marqué à la His tag.
    Séquence
    Met1-Lys177
    Attributs du produit
    A DNA sequence encoding theHuman MeCP2 protein (P51608) (Met1-Lys177) was expressed with a N-His .
    Pureté
    >95 % as determined by reducing SDS-PAGE.
    Top Product
    Discover our top product MECP2 Protéine
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Buffer
    Lyophilized from sterile PBS, pH 7.4.
    Stock
    4 °C,-20 °C,-80 °C
    Stockage commentaire
    Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
    Date de péremption
    12 months
  • Antigène
    MECP2 (Methyl CpG Binding Protein 2 (MECP2))
    Autre désignation
    MeCP2 (MECP2 Produits)
    Synonymes
    AUTSX3 Protein, MRX16 Protein, MRX79 Protein, MRXS13 Protein, MRXSL Protein, PPMX Protein, RS Protein, RTS Protein, RTT Protein, 1500041B07Rik Protein, BB130002 Protein, D630021H01Rik Protein, Mbd5 Protein, WBP10 Protein, wu:fk96a04 Protein, zgc:111857 Protein, methyl-CpG binding protein 2 Protein, methyl CpG binding protein 2 Protein, methyl-CpG binding protein 2 S homeolog Protein, MECP2 Protein, Mecp2 Protein, mecp2 Protein, mecp2.S Protein
    Sujet

    Background: Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Mediates transcriptional repression through interaction with histone deacetylase and the corepressor SIN3A. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC).

    Synonym: MeCp-2 protein

    Poids moléculaire
    19 kDa
    UniProt
    P51608
    Pathways
    Inositol Metabolic Process, Chromatin Binding, Synaptic Membrane
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