RAD51 Protein (AA 2-339) (His tag)

N° du produit ABIN7505246

Cette protéine Recombinant RAD51 est exprimée dans Escherichia coli (E. coli).

Aperçu rapide pour RAD51 Protein (AA 2-339) (His tag) (ABIN7505246)

Antigène: RAD51 (DNA Repair Protein Homolog 1 (RAD51))

Type de proteíne: Recombinant

Origine: Humain

Source: Escherichia coli (E. coli)

Pureté: > 95 % as determined by reducing SDS-PAGE.

Détail du produit

Attributs du protein: AA 2-339

Purification/Conjugué: Cette RAD51 protéine est marqué à la His tag.

Séquence: Ala 2-Asp 339

Attributs du produit: A DNA sequence encoding the Human Rad51 protein (Q06609) (Ala 2-Asp 339) was expressed with a N-His.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Date de péremption: 12 months

Détail du antigène

Antigène: RAD51 (DNA Repair Protein Homolog 1 (RAD51))

Autre désignation: Rad51

Sujet:

Abbreviation: Rad51

Target Synonym: DNA repair protein RAD51 homolog 1,RAD51, HsRAD51,hRAD51

Background: Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange (PubMed:26681308). Part of a PALB2-scaffolded HR complex containing BRCA2 and RAD51C and which is thought to play a role in DNA repair by HR. Plays a role in regulating mitochondrial DNA copy number under conditions of oxidative stress in the presence of RAD51C and XRCC3.

Poids moléculaire:

Calculated MW: 37.07 kDa

Observed MW: 38 kDa

UniProt: Q06609

Pathways: Réparation de l'ADN