Lamin B1 Protein (LMNB1) (AA 387-587) (His tag)

N° du produit ABIN7505477

Détail du produit

Antigène: Lamin B1 (LMNB1)

Type de proteíne: Recombinant

Attributs du protein: AA 387-587

Origine: Rat

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette Lamin B1 protéine est marqué à la His tag.

Séquence: Arg387-Met587

Attributs du produit: A DNA sequence encoding the Rat Lamin B1 (P70615-1) (Arg387-Met587) was expressed with a polyhistidine tag at the N-terminus.

Pureté: >90 % as determined by reducing SDS-PAGE.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Date de péremption: 12 months

Détail du antigène

Antigène: Lamin B1 (LMNB1)

Autre désignation: Lamin B1 (LMNB1 Produits)

Synonymes: MGC52550 Protein, Lamin-L(I) Protein, lamin-b Protein, lmn Protein, lmn2 Protein, lmnb Protein, LMNB1 Protein, ADLD Protein, LMN Protein, LMN2 Protein, LMNB Protein, fc06g01 Protein, wu:fc06g01 Protein, lamin B1 L homeolog Protein, lamin B1 Protein, lmnb1.L Protein, lmnb1 Protein, LMNB1 Protein, Lmnb1 Protein

Sujet:

Background: The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. This gene encodes one of the two B type proteins, B1. Alternative splicing results in transcript variants and a duplication of this gene is associated with autosomal dominant adult-onset leukodystrophy (ADLD).

Synonym: ADLD,lamin B1,Lamin-B1,LMN,LMN2,LMNB,Lmnb1,LMNB1,MGC111419,OTTHUMP00000159218

Poids moléculaire: 22.1 kDa

Pathways: Apoptose, Caspase Cascade in Apoptosis