CD5 Protein (CD5) (AA 25-368) (His tag)

N° du produit ABIN7505555

Détail du produit

Antigène: CD5

Type de proteíne: Recombinant

Attributs du protein: AA 25-368

Origine: Rat

Source: Escherichia coli (E. coli)

Purification/Conjugué: Cette CD5 protéine est marqué à la His tag.

Séquence: Ser 25-Pro 368

Attributs du produit: A DNA sequence encoding the Rat CD5 / Cluster of Differentiation 5 protein (P51882) (Ser 25-Pro 368) was expressed with N-His tag.

Pureté: > 95 % as determined by reducing SDS-PAGE.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01 % Tween80 are added as protectants before lyophilization.

Stock: 4 °C,-20 °C,-80 °C

Stockage commentaire: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.

Date de péremption: 12 months

Détail du antigène

Antigène: CD5

Autre désignation: CD5 (CD5 Produits)

Synonymes: CD5 Protein, Ly-1 Protein, Ly-12 Protein, Ly-A Protein, Lyt-1 Protein, LEU1 Protein, T1 Protein, CD5 molecule Protein, CD5 antigen Protein, CD5 molecule like Protein, Cd5 molecule Protein, CD5 Protein, Cd5 Protein, CD5L Protein

Sujet:

Abbreviation: CD5

Target Synonym: T-cell surface glycoprotein CD5,Cd5,

Background: The cluster of differentiation (CD) system is commonly used as cell markers in immunophynotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. CD5 is a member of the CD system. CD5 was found to be widely distributed in T-cells and B1 cells which is a subset of IgM-secreting B cells. CD5 also was found expressed in small lymphocytic lymphoma, hairy cell leukaemia and mantle cell lymphoma cells. CD5 serves to weaken the activating stimulus from the BCR so that the B1 cells can only reflect to the very strong stimuli but not the normal tissue proteins.

Poids moléculaire:

Calculated MW: 37.73 kDa

Observed MW: 42 kDa

UniProt: P51882