VEGF121 Protein (AA 1-147) (His tag)
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- Antigène Voir toutes VEGF121 Protéines
- VEGF121 (Vascular Endothelial Cell Growth Factor 121 (VEGF121))
- Type de proteíne
- Recombinant
- Attributs du protein
- AA 1-147
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Origine
- Humain
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette VEGF121 protéine est marqué à la His tag.
- Séquence
- Met1-Arg147
- Attributs du produit
- A DNA sequence encoding theHuman VEGF121 protein (P15692-9) (Met1-Arg147) was expressed with a C-His.
- Pureté
- >95 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product VEGF121 Protéine
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Buffer
- Lyophilized from sterile PBS, pH 7.4.
- Stock
- 4 °C,-20 °C,-80 °C
- Stockage commentaire
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
- Date de péremption
- 12 months
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- Antigène
- VEGF121 (Vascular Endothelial Cell Growth Factor 121 (VEGF121))
- Autre désignation
- VEGF121 (VEGF121 Produits)
- Sujet
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Background: Growth factor active in angiogenesis, vasculogenesis and endothelial cell growth. Induces endothelial cell proliferation, promotes cell migration, inhibits apoptosis and induces permeabilization of blood vessels. Binds to the FLT1/VEGFR1 and KDR/VEGFR2 receptors, heparan sulfate and heparin. NRP1/Neuropilin-1 binds isoforms VEGF-165 and VEGF-145. Isoform ', ' binds to KDR but does not activate downstream signaling pathways, does not activate angiogenesis and inhibits tumor growth. Binding to NRP1 receptor initiates a signaling pathway needed for motor neuron axon guidance and cell body migration, including for the caudal migration of facial motor neurons from rhombomere 4 to rhombomere 6 during embryonic development. Also binds the DEAR/FBXW7-AS1 receptor.
Synonym: VEGF-A,Vascular permeability factor,VPF,VEGFA
- Poids moléculaire
- 17.2 kDa
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