CLEC10A Protein (His tag)

N° du produit ABIN7534241

Détail du produit

Antigène: CLEC10A (C-Type Lectin Domain Family 10, Member A (CLEC10A))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette CLEC10A protéine est marqué à la His tag.

Fonction: Recombinant Human CD301 Protein

Séquence: QNSKFQRDLV TLRTDFSNFT SNTVAEIQAL TSQGSSLEET IASLKAEVEG FKQERQAGVS ELQEHTTQKA HLGHCPHCPS VCVPVHSEML LRVQQLVQDL KKLTCQVATL NNNASTEGTC CPVNWVEHQD SCYWFSHSGM SWAEAEKYCQ LKNAHLVVIN SREEQNFVQK YLGSAYTWMG LSDPEGAWKW VDGTDYATGF QNWKPGQPDD WQGHGLGGGE DCAHFHPDGR WNDDVCQRPY HWVCEAGLGQ TSQESH

Specificité: Gln61-His316

Pureté: > 90 % by SDS-PAGE.

Stérilité: 0.22 μm filtered

niveau d'endotoxine: < 1.0 EU/μg of the protein by LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.

Buffer: Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.

Stock: -20 °C,-80 °C

Stockage commentaire: Store the lyophilized protein at -20°C to -80 °C for long term.
After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.

Détail du antigène

Antigène: CLEC10A (C-Type Lectin Domain Family 10, Member A (CLEC10A))

Autre désignation: CD301 (CLEC10A Produits)

Synonymes: CLEC10A Protein, CD301 Protein, CLECSF13 Protein, CLECSF14 Protein, HML Protein, HML2 Protein, MGL Protein, CD301a Protein, M-ASGP-BP-1 Protein, Mgl Protein, Mgl1 Protein, Mgll Protein, C-type lectin domain family 10 member A Protein, C-type lectin domain containing 10A Protein, C-type lectin domain family 10, member A Protein, LOC607405 Protein, CLEC10A Protein, Clec10a Protein

Sujet:

Description: CLEC10A, also known as macrophage galactose/N-acetyl-galactosamine (GalNAc) specific lectin (MGL), CD301, DC-ASGPR, and HML, is a 40 kDa type II transmembrane glycoprotein that belongs to the C-type lectin family. C-type lectin family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. CLEC10A is expressed on macrophages and related cells of myeloid origins, particularly immature dendritic cells (DCs). CLEC10A plays a protective role against colitis by effectively inducing IL-10 production by colonic lamina propria macrophages in response to invading commensal bacteria.

Name: CLEC10A,CD301,CLECSF13,CLECSF14,HML,HML2,MGL

ID gène: 10462

UniProt: Q8IUN9