Ephrin B1 Protein (EFNB1) (His tag)

N° du produit ABIN7533927

Détail du produit

Antigène: Ephrin B1 (EFNB1)

Type de proteíne: Recombinant

Activité biologique: Active

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette Ephrin B1 protéine est marqué à la His tag.

Fonction: Active Recombinant Human Ephrin-B1/EFNB1 Protein

Séquence: LAKNLEPVSW SSLNPKFLSG KGLVIYPKIG DKLDIICPRA EAGRPYEYYK LYLVRPEQAA ACSTVLDPNV LVTCNRPEQE IRFTIKFQEF SPNYMGLEFK KHHDYYITST SNGSLEGLEN REGGVCRTRT MKIIMKVGQD PNAVTPEQLT TSRPSKEADN TVKMATQAPG SRGSLGDSDG KHETVNQEEK SGPGASGGSS GDPDG

Specificité: Leu28-Gly232

Pureté: > 95 % by SDS-PAGE.

Stérilité: 0.22 μm filtered

niveau d'endotoxine: < 0.1 EU/μg of the protein by LAL method.

Biological Activity Comment: Measured by its binding ability in a functional ELISA. Immobilized Human EFNB1 at 0.5 μg/mL (100 μL/well) can bind Mouse EPHB3 with a linear range of 0.1-3.5 ng/mL.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.

Buffer: Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.

Stock: -20 °C,-80 °C

Stockage commentaire: Store the lyophilized protein at -20°C to -80 °C for long term.
After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.

Détail du antigène

Antigène: Ephrin B1 (EFNB1)

Autre désignation: Ephrin-B1/EFNB1 (EFNB1 Produits)

Synonymes: EFNB1 Protein, LERK2 Protein, Cek5-L Protein, EFL-3 Protein, Elk-L Protein, Epl2 Protein, Eplg2 Protein, LERK-2 Protein, Lerk2 Protein, Stra1 Protein, CFND Protein, CFNS Protein, EFL3 Protein, EPLG2 Protein, cfnd Protein, cfns Protein, efl3 Protein, efnb1-A Protein, ephrinB1 Protein, eplg2 Protein, lerk2 Protein, ephrin B1 Protein, ephrin-B1 Protein, ephrin-B1 L homeolog Protein, EFNB1 Protein, Efnb1 Protein, efnb1 Protein, efnb1.L Protein

Sujet:

Description: Ephrin-B1 also known as EFNB1, is a member of the ephrin family. The transmembrane- associated ephrin ligands and their Eph family of receptor tyrosine kinases are expressed by cells of the SVZ. Eph/ephrin interactions are implicated in axon guidance, neural crest cell migration, establishment of segmental boundaries, and formation of angiogenic capillary plexi. Eph receptors and ephrins are divided into two subclasses, A and B, based on binding specificities. Ephrin subclasses are further distinguished by their mode of attachment to the plasma membrane: ephrin-A ligands bind EphA receptors and are anchored to the plasma membrane via a glycosylphosphatidylinositol (GPI) linkage, whereas ephrin-B ligands bind EphB receptors and are anchored via a transmembrane domain. An exception is the EphA4 receptor, which binds both subclasses of ephrins.

Name: EFNB1,CFND,CFNS,EFB1,EFL3,EPLG2,Elk-L,LERK2,ephrin-B1

ID gène: 1947

UniProt: P98172

Pathways: Signalisation RTK