Granulin Protein (GRN) (His tag)

N° du produit ABIN7520050

Détail du produit

Antigène: Granulin (GRN)

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette Granulin protéine est marqué à la His tag.

Fonction: Recombinant Human Progranulin/PGRN/GRN Protein

Séquence: TRCPDGQFCP VACCLDPGGA SYSCCRPLLD KWPTTLSRHL GGPCQVDAHC SAGHSCIFTV SGTSSCCPFP EAVACGDGHH CCPRGFHCSA DGRSCFQRSG NNSVGAIQCP DSQFECPDFS TCCVMVDGSW GCCPMPQASC CEDRVHCCPH GAFCDLVHTR CITPTGTHPL AKKLPAQRTN RAVALSSSVM CPDARSRCPD GSTCCELPSG KYGCCPMPNA TCCSDHLHCC PQDTVCDLIQ SKCLSKENAT TDLLTKLPAH TVGDVKCDME VSCPDGYTCC RLQSGAWGCC PFTQAVCCED HIHCCPAGFT CDTQKGTCEQ GPHQVPWMEK APAHLSLPDP QALKRDVPCD NVSSCPSSDT CCQLTSGEWG CCPIPEAVCC SDHQHCCPQG YTCVAEGQCQ RGSEIVAGLE KMPARRASLS HPRDIGCDQH TSCPVGQTCC PSLGGSWACC QLPHAVCCED RQHCCPAGYT CNVKARSCEK EVVSAQPATF LARSPHVGVK DVECGEGHFC HDNQTCCRDN RQGWACCPYR QGVCCADRRH CCPAGFRCAA RGTKCLRREA PRWDAPLRDP ALRQLL

Specificité: Thr18-Leu593

Pureté: > 90 % by SDS-PAGE.

Stérilité: 0.22 μm filtered

niveau d'endotoxine: < 0.1 EU/μg of the protein by LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.

Buffer: Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.

Stock: -20 °C,-80 °C

Stockage commentaire: Store the lyophilized protein at -20°C to -80 °C for long term.
After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.

Détail du antigène

Antigène: Granulin (GRN)

Autre désignation: Progranulin/PGRN/GRN (GRN Produits)

Synonymes: GRN Protein, grn Protein, wu:fb11g12 Protein, wu:fj18f05 Protein, MGC53354 Protein, DKFZp459H066 Protein, CLN11 Protein, GEP Protein, GP88 Protein, PCDGF Protein, PEPI Protein, PGRN Protein, epithelin Protein, acrogranin Protein, granulin precursor Protein, granulin a Protein, Granulins Protein, granulin L homeolog Protein, granulin Protein, GRN Protein, grna Protein, grn Protein, grn.L Protein, granulin Protein, ORF1 granulin Protein, Grn Protein

Sujet:

Description: Granulins are a family of secreted, glycosylated peptides that are cleaved from a single precursor protein with 7.5 repeats of a highly conserved 12-cysteine granulin/epithelin motif. The 88 kDa precursor protein, progranulin, is also called proepithelin and PC cell-derived growth factor. Cleavage of the signal peptide produces mature granulin which can be further cleaved into a variety of active, 6 kDa peptides. These smaller cleavage products are named granulin A, granulin B, granulin C, etc. Epithelins 1 and 2 are synonymous with granulins A and B, respectively. Both the peptides and intact granulin protein regulate cell growth. However, different members of the granulin protein family may act as inhibitors, stimulators, or have dual actions on cell growth. Granulin family members are important in normal development, wound healing, and tumorigenesis.

Name: CLN11, GEP, GP88, PCDGF, PEPI, PGRN,GRN, CLN11, granulins,GEP,GP88,PCDGF,PEPI,PGRN,granulins

ID gène: 2896

UniProt: P28799