NCR1 Protein (rFc Tag)

N° du produit ABIN7535765

Détail du produit

Antigène: NCR1 (Natural Cytotoxicity Triggering Receptor 1 (NCR1))

Type de proteíne: Recombinant

Origine: Souris

Source: HEK-293 Cells

Purification/Conjugué: Cette NCR1 protéine est marqué à la rFc Tag.

Fonction: Recombinant Mouse NCR1/CD335 Protein

Séquence: QRINTEKETL PKPIIWAKPS IMVTNGNSVN IWCQGAQSAS EYQLYFEGSF FALERPKPSR SMNKVRFFIS QMTSHTAGIY TCFYQSGELW SKSSNPLKLV VTGLYDTPNL WVYPRPEVTL GENVTFFCQL KTATSKFFLL KERGSNHIQN KYGNIQAEFP MGPVTRAHRG TYRCFGSYND YAWSFPSEPV TLLITGGVEN SSLAPTDPTS SLDYWEFDLS TNESGLQKDS AFWDHTTQN

Specificité: Gln17-Asn255

Pureté: > 95 % by SDS-PAGE.

Stérilité: 0.22 μm filtered

niveau d'endotoxine: <0.1EU/μg

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.

Buffer: Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.

Stock: -20 °C,-80 °C

Stockage commentaire: Store the lyophilized protein at -20°C to -80°C for 12 months.|After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.

Détail du antigène

Antigène: NCR1 (Natural Cytotoxicity Triggering Receptor 1 (NCR1))

Autre désignation: NCR1/CD335 (NCR1 Produits)

Synonymes: CD335 Protein, LY94 Protein, NK-p46 Protein, NKP46 Protein, Ly94 Protein, NKp46 Protein, KILR-1 Protein, Nk-p46 Protein, Nkp46 Protein, natural cytotoxicity triggering receptor 1 Protein, NCR1 Protein, Ncr1 Protein

Sujet:

Description: NCR1, also known as NK-p46 and CD335, is a natural cytotoxicity receptor(NCR). NCRs are type I transmembrane proteins with 1-2 extracellular immunoglobulin domains, a transmembrane domain containing a positively charged amino acid residue, and a short cytoplasmic tail. All are expressed almost exclusively by NK cells and play a major role in triggering NK-mediated killing of most tumor cell lines. NKp46 has two extracellular Ig-like domains followed by a ~40 residue stalk region, a type I transmembrane domain, and a short cytoplasmic tail. NKp46 has been implicated in NK cell-mediated lysis of several autologous tumor cells, pathogen-infected cell lines, and mononuclear phagocytes infected with an intracellular bacterium.

Name: Ly94,NKp46,Ncr1

ID gène: 17086

UniProt: Q8C567

Pathways: Regulation of Leukocyte Mediated Immunity