SERPINC1 Protein (His tag)
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- Antigène Voir toutes SERPINC1 Protéines
- SERPINC1 (Serpin Family C Member 1 (SERPINC1))
- Type de proteíne
- Recombinant
- Activité biologique
- Active
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Origine
- Humain
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Source
- HEK-293 Cells
- Purification/Conjugué
- Cette SERPINC1 protéine est marqué à la His tag.
- Fonction
- Active Recombinant Human Serpin C1/Antithrombin-III Protein
- Séquence
- HGSPVDICTA KPRDIPMNPM CIYRSPEKKA TEDEGSEQKI PEATNRRVWE LSKANSRFAT TFYQHLADSK NDNDNIFLSP LSISTAFAMT KLGACNDTLQ QLMEVFKFDT ISEKTSDQIH FFFAKLNCRL YRKANKSSKL VSANRLFGDK SLTFNETYQD ISELVYGAKL QPLDFKENAE QSRAAINKWV SNKTEGRITD VIPSEAINEL TVLVLVNTIY FKGLWKSKFS PENTRKELFY KADGESCSAS MMYQEGKFRY RRVAEGTQVL ELPFKGDDIT MVLILPKPEK SLAKVEKELT PEVLQEWLDE LEEMMLVVHM PRFRIEDGFS LKEQLQDMGL VDLFSPEKSK LPGIVAEGRD DLYVSDAFHK AFLEVNEEGS EAAASTAVVI AGRSLNPNRV TFKANRPFLV FIREVPLNTI IFMGRVANPC VK
- Specificité
- His33-Lys464
- Pureté
- > 95 % by SDS-PAGE.
- Stérilité
- 0.22 μm filtered
- niveau d'endotoxine
- < 0.1 EU/μg of the protein by LAL method.
- Biological Activity Comment
- Measured by its ability to inhibit Recombinant Human Coagulation Factor II/Thrombin cleavage of a fluorogenic peptide substrate Boc-VPR-AMC. The IC50 value is <0.48 nM.
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- Discover our top product SERPINC1 Protéine
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Serpin Family C Member 1 (SERPINC1) (AA 1-259) protein (GST tag)
SERPINC1 Origine: Humain Hôte: Wheat germ Recombinant WB, ELISA, AP, AA
Serpin Family C Member 1 (SERPINC1) (AA 33-464) protein (His tag)Crystallography grade SERPINC1 Origine: Humain Hôte: Cellules d'insectes Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
Serpin Family C Member 1 (SERPINC1) (AA 33-465) protein (His tag)Crystallography grade SERPINC1 Origine: Souris Hôte: Cellules d'insectes Recombinant >95 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. SDS, WB, ELISA, Crys
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
- Buffer
- Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
- Stock
- -20 °C,-80 °C
- Stockage commentaire
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Store the lyophilized protein at -20°C to -80 °C for long term.
After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.
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- Antigène
- SERPINC1 (Serpin Family C Member 1 (SERPINC1))
- Autre désignation
- Serpin C1/Antithrombin-III (SERPINC1 Produits)
- Synonymes
- AT3 Protein, AT3D Protein, ATIII Protein, THPH7 Protein, SERPINC1 Protein, DKFZp470C1733 Protein, AI114908 Protein, At-3 Protein, At3 Protein, ANTITHROMBIN, AT-III Protein, AT-III Protein, serpin family C member 1 Protein, antithrombin-III Protein, serine (or cysteine) peptidase inhibitor, clade C (antithrombin), member 1 Protein, SERPINC1 Protein, CpipJ_CPIJ000472 Protein, CpipJ_CPIJ013111 Protein, Serpinc1 Protein
- Sujet
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Description: The protein is a plasma protease inhibitor and a member of the serpin superfamily. This protein inhibits thrombin as well as other activated serine proteases of the coagulation system, and it regulates the blood coagulation cascade. The protein includes two functional domains: the heparin binding-domain at the N-terminus of the mature protein, and the reactive site domain at the C-terminus. The inhibitory activity is enhanced by the presence of heparin. More than 120 mutations have been identified for this gene, many of which are known to cause antithrombin-III deficiency.
Name: AT3, AT3D, ATIII, THPH7,SERPINC1,AT3D,ATIII,THPH7
- ID gène
- 462
- UniProt
- P01008
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