WFDC2 Protein (Fc Tag)

N° du produit ABIN7536542

Détail du produit

Antigène: WFDC2 (WAP Four-Disulfide Core Domain 2 (WFDC2))

Type de proteíne: Recombinant

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette WFDC2 protéine est marqué à la Fc Tag.

Fonction: Recombinant Human WFDC2/HE4/WAP5 Protein

Séquence: EKTGVCPELQ ADQNCTQECV SDSECADNLK CCSAGCATFC SLPNDKEGSC PQVNINFPQL GLCRDQCQVD SQCPGQMKCC RNGCGKVSCV TPNF

Specificité: Glu31-Phe124

Pureté: > 97 % by SDS-PAGE.

Stérilité: 0.22 μm filtered

niveau d'endotoxine: < 0.01EU/μg

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.

Concentration: 1.33 mg/mL

Buffer: Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.

Stock: -20 °C,-80 °C

Stockage commentaire: Store the lyophilized protein at -20°C to -80°C for 12 months.|After reconstitution, the protein solution is stable at -20°C for 3 months, at 2-8°C for up to 1 week.

Détail du antigène

Antigène: WFDC2 (WAP Four-Disulfide Core Domain 2 (WFDC2))

Autre désignation: WFDC2/HE4/WAP5 (WFDC2 Produits)

Synonymes: WFDC3 Protein, WFDC2 Protein, si:ch211-153a8.3 Protein, EDDM4 Protein, HE4 Protein, WAP5 Protein, dJ461P17.6 Protein, 1600023A02Rik Protein, re4 Protein, CE4 Protein, BE-20 Protein, WAP four-disulfide core domain 2 Protein, WFDC2 Protein, wfdc2 Protein, Wfdc2 Protein

Sujet:

Description: WAP four-disulfide core domain protein 2, also known as Epididymal secretory protein E4, Major epididymis-specific protein E4, Putative protease inhibitor WAP5, WFDC2 and HE4, is a secreted protein that contains two WAP domains. WFDC2 / HE4 is a member of a family of stable 4-disulfide core proteins that are secreted at high levels. It is expressed in a number of normal tissues, including male reproductive system, regions of the respiratory tract and nasopharynx. It is highly expressed in a number of tumors cells lines, such ovarian, colon, breast, lung and renal cells lines. Initially described as being exclusively transcribed in the epididymis. WFDC2 may be a component of the innate immune defences of the lung, nasal and oral cavities and suggest that WFDC2 functions in concert with related WAP domain containing proteins in epithelial host defence. WFDC2 re-expression in lung carcinomas may prove to be associated with tumour type and should be studied in further detail. Mammary gland expression of tammar WFDC2 during the course of lactation showed WFDC2 was elevated during pregnancy, reduced in early lactation and absent in mid-late lactation. WFDC2 / HE4 can undergo a complex series of alternative splicing events that can potentially yield five distinct WAP domain containing protein isoforms.

Name: HE4, WAP5, EDDM4, dJ461P17.6,VEGFR-3,FLT-4,WFDC2

ID gène: 10406

UniProt: Q14508