WIF1 Protein (Gln166Lys) (His tag)

N° du produit ABIN7534198

Détail du produit

Antigène: WIF1 (WNT Inhibitory Factor 1 (WIF1))

Type de proteíne: Recombinant

Attributs du protein: Gln166Lys

Origine: Humain

Source: HEK-293 Cells

Purification/Conjugué: Cette WIF1 protéine est marqué à la His tag.

Fonction: Recombinant Human WIF-1(Q166K) Protein

Séquence: GPPQEESLYL WIDAHQARVL IGFEEDILIV SEGKMAPFTH DFRKAQQRMP AIPVNIHSMN FTWQAAGQAE YFYEFLSLRS LDKGIMADPT VNVPLLGTVP HKASVVQVGF PCLGKQDGVA AFEVDVIVMN SEGNTILKTP QNAIFFKTCQ QAECPGGCRN GGFCNERRIC ECPDGFHGPH CEKALCTPRC MNGGLCVTPG FCICPPGFYG VNCDKANCST TCFNGGTCFY PGKCICPPGL EGEQCEISKC PQPCRNGGKC IGKSKCKCSK GYQGDLCSKP VCEPGCGAHG TCHEPNKCQC QEGWHGRHCN KRYEASLIHA LRPAGAQLRQ HTPSLKKAEE RRDPPESNYI W

Specificité: Gly29-Trp379(Q166K)

Pureté: > 97 % by SDS-PAGE.

Stérilité: 0.22 μm filtered

niveau d'endotoxine: < 0.1 EU/μg of the protein by LAL method.

Information d'application

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid votex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1 % BSA, 5 % HSA, 10 % FBS or 5 % Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.

Buffer: Lyophilized from a 0.22 μm filtered solution of 20 mM HAc-NaAc,150 mM NaCl,0.5 % CHAPS, pH 6.0.

Stock: -20 °C,-80 °C

Stockage commentaire: Store the lyophilized protein at -20°C to -80 °C for long term.
After reconstitution, the protein solution is stable at -20 °C for 3 months, at 2-8 °C for up to 1 week.

Détail du antigène

Antigène: WIF1 (WNT Inhibitory Factor 1 (WIF1))

Autre désignation: WIF-1 (WIF1 Produits)

Synonymes: shf Protein, GB10372 Protein, wif-1 Protein, WIF1 Protein, WIF-1 Protein, AW107799 Protein, zgc:110507 Protein, protein shifted Protein, wnt inhibitory factor 1 Protein, WNT inhibitory factor 1 Protein, Wnt inhibitory factor 1 Protein, WNT inhibitory factor 1 S homeolog Protein, LOC552805 Protein, CpipJ_CPIJ003761 Protein, wif1 Protein, WIF1 Protein, Wif1 Protein, LOC100511326 Protein, wif1.S Protein

Sujet:

Description: WIF (Wnt Inhibitory Factor) is a secreted protein that binds to Wnt proteins and inhibits their activity. WIF is extracellular signaling molecules that play a role in embryonic development. This protein contains a WNT inhibitory factor (WIF) domain and five epidermal growth factor (EGF)-like domains, and is thought to be involved in mesoderm segmentation.. WIF-1 is implicated as an early event tumor suppressor in cancers of the prostate, breast, lung and bladder. However, WIF-1's role in carcinogenesis may not be that simple since in other cancer types, such as colon adenocarcinoma, WIF facilitates tumorigenesis.

Name: WIF-1,WIF1

ID gène: 11197

UniProt: Q9Y5W5

Pathways: Signalisation WNT, Positive Regulation of fat Cell Differentiation