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IL-33 Protéine

IL33 Origine: Humain Hôte: Escherichia coli (E. coli) Recombinant > 97 % by SDS-PAGE and HPLC analyses. Active
N° du produit ABIN871798
  • Antigène Voir toutes IL-33 (IL33) Protéines
    IL-33 (IL33) (Interleukin 33 (IL33))
    Type de proteíne
    Recombinant
    Activité biologique
    Active
    Origine
    • 22
    • 15
    • 3
    • 2
    • 1
    • 1
    • 1
    Humain
    Source
    • 29
    • 8
    • 2
    • 2
    • 1
    Escherichia coli (E. coli)
    Séquence
    MSITGISPIT EYLASLSTYN DQSITFALED ESYEIYVEDL KKDEKKDKVL LSYYESQHPS NE SGDGVDGK MLMVTLSPTK DFWLHANNKE HSVELHKCEK PLPDQAFFVL HNMHSNCVSF ECKTDPGVFI GVKDNHLALI KVDSSENLCT ENILFKLSET
    Pureté
    > 97 % by SDS-PAGE and HPLC analyses.
    Stérilité
    0.2 μm filtered
    niveau d'endotoxine
    Less than 1EU/µg of rHuIL-33 as determined by LAL method.
    Top Product
    Discover our top product IL33 Protéine
  • Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at < -20° C. Further dilutions should be made in appropriate buffered solutions.
    Stock
    4 °C/-20 °C
  • Antigène
    IL-33 (IL33) (Interleukin 33 (IL33))
    Autre désignation
    IL-33 (IL33 Produits)
    Synonymes
    IL33 Protein, C9orf26 Protein, DVS27 Protein, IL1F11 Protein, NF-HEV Protein, NFEHEV Protein, RP11-575C20.2 Protein, 9230117N10Rik Protein, Il-33 Protein, Il1f11 Protein, RGD1311155 Protein, interleukin 33 Protein, IL33 Protein, Il33 Protein
    Sujet
    IL33, also known as NFHEV and DVS 27, is a 30 kDa proinflammatory protein that may also regulate gene transcription. IL33 is constitutively expressed in smooth muscle and airway epithelia. It is upregulated in arterial smooth muscle, dermal fibroblasts, and keratinocytes following IL1alpha or IL1beta stimulation. IL-33 shares structural and functional characteristics with the IL-1 cytokine family. It binds and signals through the IL-1RL1/ST2 receptor activating NF-kappaB and MAP kinases. IL-33 induces production of TH2 cell related cytokines, including IL-4, IL-5 and IL-13, and exerts multiple inflammation related bioactivities.
    Pathways
    Production of Molecular Mediator of Immune Response
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