TCEB2 Protein (AA 1-118)

N° du produit ABIN935006

Détail du produit

Antigène: TCEB2 (Transcription Elongation Factor B (SIII), Polypeptide 2 (18kDa, Elongin B) (TCEB2))

Type de proteíne: Recombinant

Attributs du protein: AA 1-118

Origine: Humain

Source: Escherichia coli (E. coli)

Application: SDS-PAGE (SDS)

Séquence: MDVFLMIRRH KTTIFTDAKE SSTVFELKRI VEGILKRPPD EQRLYKDDQL LDDGKTLGEC GFTSQTARPQ APATVGLAFR ADDTFEALCI EPFSSPPELP DVMKPQDSGS SANEQAVQ

Attributs du produit: Purified recombinant Human Elongin B protein
Expression System: E.coli
Molecular weight on SDS-PAGE will appear higher.

Pureté: > 95 % pure

Information d'application

Indications d'application: Elongin B protein has been used in SDS PAGE and may be suitable for use in other assays to be determined by the end user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Supplied as a liquid in 20 mM Tris-HCl buffer, pH 8.0, containing 0 mM DTT, 0.0 mM PMSF, and 20 % glycerol.

Agent conservateur: Dithiothreitol (DTT)

Précaution d'utilisation: This product contains Dithiothreitol: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze/thaw cycles.

Stock: RT/-20 °C

Stockage commentaire: Store at 4 °C for short term storage (1/2 weeks). Aliquot and store at -20 °C or - 70 °C for long term storage.

Détail du antigène

Antigène: TCEB2 (Transcription Elongation Factor B (SIII), Polypeptide 2 (18kDa, Elongin B) (TCEB2))

Autre désignation: Elongin B (TCEB2 Produits)

Synonymes: 0610040H15Rik Protein, cb162 Protein, wu:fb47e08 Protein, ELOB Protein, SIII Protein, elongin B Protein, Elob Protein, elob Protein, ELOB Protein

Sujet: Elongin B , also known as TCEB2, is a subunit of the transcription factor B (SIII) complex. The SIII complex is a heterotrimer consisting of a transcriptionally active subunit (A) and two regulatory subunits (B and C). It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. The von Hippel-Lindau tumor suppressor protein (pVHL) binds to elongins B and C, and thereby inhibits transcription elongation. Recombinant TCEB2 was expressed as insoluble protein aggregate in E. coli and purified by conventional chromatography, after refolding of the isolated inclusion bodies in a renaturation buffer.
Alternative Names: Elongin B protein, Transcription elongation factor B polypeptide 2 protein, Elongin 18 kDa subunit protein, SIII p18 protein, TCEB 2 protein, EloB protein, EloB protein, RNA polymerase II transcription factor SIII subunit B protein, Transcription elongation factor B (SIII) polypeptide 2., TCEB2 protein

Poids moléculaire: 13.1 kDa (118 AA)

Pathways: SARS-CoV-2 Protein Interactome