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anti-Human PIK3R6 Anticorps:
anti-Mouse (Murine) PIK3R6 Anticorps:
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Our findings suggest that p84 (Montrer PPP1R12C Anticorps) binding to p110gamma (Montrer PIK3CG Anticorps) may represent a novel negative feedback signal that terminates PI3Kgamma (Montrer PIK3CG Anticorps) activity.
expression and activities of PI3Kgamma (Montrer PIK3CG Anticorps) are modified differently by p87 and p101 (Montrer PIK3R5 Anticorps) in vitro and in living cells, arguing for specific regulatory roles of the non-catalytic subunits in the differentiation of PI3Kgamma (Montrer PIK3CG Anticorps) signaling pathways.
knockdown of p84 (Montrer PPP1R12C Anticorps) in MDA-MB-231 cells enhanced Akt (Montrer AKT1 Anticorps) phosphorylation and lung colonization
GPCR (Montrer NMUR1 Anticorps) activation of Ras and PI3Kc in neutrophils depends on PLCb2 (Montrer PLCb2 Anticorps)/b3 and the RasGEF RasGRP4 (Montrer RASGRP4 Anticorps).
p87PIKAP is a novel regulatory subunit of phosphoinositide 3-kinase gamma that is highly expressed in heart and interacts with PDE3B (Montrer PDE3B Anticorps) [p87PIKAP]
ablation of PI3Kgamma (Montrer PIK3CG Anticorps) reduced SDF1alpha-induced integrin activation in human EPCs and in murine Lin(-) BM-derived progenitor cells
RACK1 (Montrer GNB2L1 Anticorps) regulates directional cell migration by acting on G betagamma at the interface with its effectors PLC (Montrer HSPG2 Anticorps) beta and PI3K gamma (Montrer PIK3CG Anticorps)
These data demonstrate PI3Kgamma (Montrer PIK3CG Anticorps)-dependent signalling downstream of IL-17RA (Montrer IL17RA Anticorps), which plays a pivotal role in regulating IL-17 (Montrer IL17A Anticorps) production in T cells.
GPCR (Montrer GPBAR1 Anticorps) activation of Ras and PI3Kc in neutrophils depends on PLCb2 (Montrer PLCb2 Anticorps)/b3 and the RasGEF RasGRP4 (Montrer RASGRP4 Anticorps).
that genetic deletion of PI3Kgamma (Montrer PIK3CG Anticorps) enhanced scratching behaviours in histamine-dependent and protease-activated receptor 2 (PAR-2 (Montrer F2RL1 Anticorps))-dependent itch.
PI3Kgamma (Montrer PIK3CG Anticorps) has a role in the induction of CXCR3 (Montrer CXCR3 Anticorps) on T cells
Results suggest that the CXCR2 (Montrer CXCR2 Anticorps) and PI3Kgamma (Montrer PIK3CG Anticorps) signaling pathway may represent a suitable target for the development of novel therapeutic strategies for human diseases characterized by vascular leakage.
Phosphoinositide 3-kinase gamma is a lipid kinase that produces the lipid second messenger phosphatidylinositol 3,4,5-trisphosphate. The kinase is composed of a catalytic subunit and one of several regulatory subunits, and is chiefly activated by G protein-coupled receptors. This gene encodes a regulatory subunit, and is distantly related to the phosphoinositide-3-kinase, regulatory subunit 5 gene which is located adjacent to this gene on chromosome 7. The orthologous protein in the mouse binds to both the catalytic subunit and to G(beta/gamma), and mediates activation of the kinase subunit downstream of G protein-coupled receptors.
PI3Kgamma adapter protein of 87 kDa
, p84 PI3K adapter protein
, p87 phosphoinositide 3-kinase gamma (PI3Kg) adapter protein
, phosphoinositide 3-kinase regulatory subunit 6
, p87 PI3K adapter protein
, phosphoinositide 3-kinase gamma adapter protein of 87 kDa
, p87 phosphoinositide 3-kinase gamma adapter